Results 81 to 90 of about 930,964 (304)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Diary

Scottish Journal of Residential Child Care, 2018
I discuss the excessive toys and presents that were expected to make up for the lack of affection in my first foster home. I compare life at home to life in care using money and love as a theme.
Olivia Khan
doaj   +1 more source

Experience and Perceptions of Changes in the Living Environment by Older People Losing Their Autonomy: A Qualitative Study in the Caribbean

Risk Management and Healthcare Policy, 2021
Rita Chammem,1,2 Serge Domi,2 Claire Della Vecchia,1 Thomas Gilbert,1,3 Anne-Marie Schott1,3 1University of Claude Bernard Lyon 1, HESPER Laboratory, Lyon, EA 7425, France; 2CRIFONDO, Caribbean Renaissance Initiative, Département de Gé ...
Chammem R, Domi S, Della Vecchia C, Gilbert T, Schott AM   +4 more
doaj  

Attachment, Fostering Parenting and Placement Stability [PDF]

, 2014
A significant number of children remain in foster care for long periods of time. Among this vulnerable population there is a high rate of placement disruption.
DeVolld, Renae L., Rickman, Myra Alicia Louise   +1 more
core  

What are the barriers to care integration for those at the advanced stages of dementia living in care homes in the UK? Health care professional perspective [PDF]

, 2016
yesPeople with advanced dementia are frequently bed-bound, doubly incontinent and able to speak only a few words. Many reside in care homes and may often have complex needs requiring efficient and timely response by knowledgeable and compassionate staff.
Elizabeth L Sampson, Forbes D. A., Gerard Leavey, Irwin Nazareth, Jane Harrington, Kathryn Lord, Kirsten Moore, Louise Jones, Michael King, Nakanishi M., Nuriye Kupeli, Pawson R., Perrar K. M., Wolfs C. A.   +13 more
core   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Developing family-based care : complexities in implementing the UN guidelines for the alternative care of children [PDF]

, 2016
In response to immense challenges facing children in out-of-home care in all parts of the world, there is a growing international trend towards the development of family-based placements for children in out-of-home care, away from large-scale ...
Cantwell, Nigel, Davidson, Jennifer C., Elsley, Susan, Milligan, Ian, Quinn, Neil   +4 more
core   +1 more source

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

Advanced Science, EarlyView.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang, Qianchun Wang, Keming Li, Guanshuo Hu, Ying Xin, Kai Tang, Bing Hu, Pengyu Du, Renwei Mao, Baohua Ji, Youhua Tan   +10 more
wiley   +1 more source

Eliminating Barriers to the Adoption of Children from Foster Care [PDF]

, 2012
For children in foster care who cannot be reunified with their families of origin, there is no question that adoption is preferable to “aging out”. Moreover, every dollar spent on adoption for a child from foster care yields three dollars in benefits ...
Hansen, Mary Eschelbach, Kamarck, Elaine, Katz, Jeff, Wilson, Julie Boatright Boatright   +3 more
core  

INB3P: A Multi‐Modal and Interpretable Co‐Attention Framework Integrating Property‐Aware Explanations and Memory‐Bank Contrastive Fusion for Blood–Brain Barrier Penetrating Peptide Discovery

Advanced Science, EarlyView.
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv, Qianyang Wu, Jian Liu, Binlu Yang, Yuanhao Li, Junlin Xu, Yajie Meng, Leyi Wei, Zilong Zhang, Quan Zou, Xiulai Li, Feifei Cui   +11 more
wiley   +1 more source