Results 131 to 140 of about 10,675,039 (377)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Homer Foundation - 2006 Annual Report [PDF]

open access: yes, 2006
Contains mission statement, board chair's and director's messages, program information, financial statements, reports from the distributions and investment committees, grants list, donors list, and list of board ...

core  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Lloyd A. Fry Foundation - 2005 Annual Report [PDF]

open access: yes, 2006
Contains mission statement, board chair's and executive director's messages, program information, grantee profiles, grants list, financial statements, grant guidelines, and lists of board members and ...

core  

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Foundation Expenses and Compensation: Interim Report 2005 [PDF]

open access: yes, 2005
Examines the 10,000 largest foundations and identifies characteristics and operating styles that affect levels of expenses and compensation, including foundation type, size, staffing, scope of activity, and direct charitable ...
Elizabeth T. Boris   +2 more
core  

FROM WINKLER’S FOUNDATION TO POPOV’S FOUNDATION

open access: yesFacta Universitatis, Series: Mechanical Engineering, 2019
In recent years, the method of dimensionality reduction (MDR) has started to figure as a very convenient tool for dealing with a wide class of elastic contact problems. The MDR modeling framework introduces an equivalent punch profile and a one-dimensional Winkler-type elastic foundation, called henceforth Popov’s foundation.
openaire   +5 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Pathos, a new landing. The Foundation Congress in Taormina. Editorial

open access: yesPathos, 2012
Editorial about the Foundation Congress in Taormina (Federdolore-SICD).
Francesco Amato, Sergio Mameli
doaj  

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