Results 101 to 110 of about 420,357 (288)
Tikrit Journal of Engineering Sciences, 2006 The role of soil-structure interaction on seismic behavior of reinforced concrete structures is investigated in this paper. Finite element approach has been adopted to model the interaction system, that consists of a reinforced concrete plane frame, soil
Mohammed N. Mahmood +1 more
doaj +1 more source
Critical issues in microbusiness finance and the role of donors . [Version Sept. 1977] [PDF]
, 1997 In the early 1990s, a consensus emerged among the leading experts in the field of small and micro business finance. It is based on three elements: The focus of projects should be on improving the entire financial sector of a given developing country; a ...
Schmidt, Reinhard H. +1 more
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Inversion and utilization of in-situ mechanical parameters of palaeochannel deposits
Yantu gongcheng xuebaoDuring the process of hydropower development in China, it is often encountered to use deep deposits or overburden as dam foundation. The causes and compositions of deposits are complex, and their physical and mechanical properties will affect the ...
DENG Chengjin 1 , ZHU Yushan 1, MIAO Zhe 1, LING Hua 2, YUAN Qiushuang 1
doaj +1 more source
Journal of Economic Geology, 2019 The Firouzeh mine is located in the Northwest of Neyshabour in the Khorasan Razavi province, Northeast of Iran, and eastern side of the Quchan-Sabzevar Cenozoic magmatic arc.
Alireza Ghiasvand +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Restoring the Bank Lending Channel of Monetary Transmission [PDF]
, 2013 This paper reports on a ‘round table’ panel discussion that took place at the 30thInternational Symposium on Money, Banking and Finance. This panel discussionwith the same title as this paper was organised by the UK’s ESRC (European andSocial Research ...
Mullineux, Andrew
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source