Results 61 to 70 of about 4,175,997 (361)

Criminal Justice Reform and Recidivism Reduction [PDF]

, 2016
This article briefly examines evidence-based approach to policymaking in criminal justice and the two conceptual pillars that serve as the foundation of this strategy: effectiveness and efficiency.
Armstrong, Barbara, Myrstol, Brad A.
core  

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Geographic Trends, Patient Characteristics, and Outcomes of Infective Endocarditis Associated With Drug Abuse in the United States From 2002 to 2016

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background There has been an increase in the prevalence of drug abuse (DA) in the national opioid epidemic. With increasing DA, there is an increased risk of infective endocarditis (IE).
Amer N. Kadri, Bryan Wilner, Adrian V. Hernandez, Georges Nakhoul, Johnny Chahine, Brian Griffin, Gosta Pettersson, Richard Grimm, Jose Navia, Steven Gordon, Samir R. Kapadia, Serge C. Harb   +11 more
doaj   +1 more source

Consistency of covid-19 trial preprints with published reports and impact for decision making: retrospective review

BMJ Medicine, 2022
Objective To assess the trustworthiness (ie, complete and consistent reporting of key methods and results between preprint and published trial reports) and impact (ie, effects of preprints on meta-analytic estimates and the certainty of evidence) of ...
Gordon Guyatt, Arnav Agarwal, Ying Wang, Dena Zeraatkar, Anila Qasim, Chirag Patel, Gabriel Rada, Romina Brignardello-Petersen, Elena Kum, Maryam Ghadimi, Reed Alexander Cunningham Siemieniuk, Ellen Cusano, Tyler Pitre, Jessica Julia Bartoszko, Matthew Adam Cooper, Gareth Leung, Faran Khalid, Zaira Escamilla, Francisca Verdugo-Paiva   +18 more
doaj   +1 more source

A Practical Introduction to Regression Discontinuity Designs: Foundations [PDF]

, 2019
In this Element and its accompanying Element, Matias D. Cattaneo, Nicolas Idrobo, and Rocio Titiunik provide an accessible and practical guide for the analysis and interpretation of Regression Discontinuity (RD) designs that encourages the use of a common set of practices and facilitates the accumulation of RD-based empirical evidence. In this Element,
arxiv   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Black holes and gravitational waves in concert - a probe of superstring cosmology [PDF]

Gen.Rel.Grav. 30 (1998) 1711-1715, 1998
Two strands of observational gravitation, one the search for astrophysical evidence of primordial black holes and the other the search for gravitational waves, may combine to provide strong evidence in favour of cosmological models based on superstring theory, the leading candidate for unifying gravity with the other fundamental forces.
arxiv   +1 more source

Oregon Parenting Education Collaborative: Helping Parents Raise Children Who Thrive [PDF]

, 2015
This report summarizes the work of the Oregon Parenting Education Collaborative during its first five years, 2010-2015. OPEC is a multi-year initiative led by The Oregon Community Foundation, The Ford Family Foundation and Oregon State University ...
Bill Graves
core  

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source