Results 71 to 80 of about 4,175,997 (361)

Maternal health research outputs and gaps in Latin America: reflections from the mapping study

open access: yesGlobalization and Health, 2017
As part of the MASCOT/WOTRO multinational team conducting the maternal health literature mapping, four Latin American researchers were particularly interested in analysing information specific to their region.
Emily Vargas-Riaño   +3 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Colorectal cancer screening with faecal testing, sigmoidoscopy or colonoscopy: a systematic review and network meta-analysis

open access: yesBMJ Open, 2019
Objective Evaluate effectiveness, harms and burdens of faecal blood testing, sigmoidoscopy and colonoscopy screening for colorectal cancer over 15 years.Design We performed an update of a Cochrane systematic review, and performed network meta-analysis ...
Per Olav Vandvik   +5 more
doaj   +1 more source

Fundamental Portfolio Outperforms the Market Portfolio [PDF]

open access: yesarXiv, 2022
There is substantial empirical evidence showing the fundamental portfolio outperforming the market portfolio. Here a theoretical foundation is laid that supports this empirical research. Assuming stock prices revert around fundamental prices with sufficient strength and symmetry, the fundamental portfolio outperforms the market portfolio in expectation.
arxiv  

Measuring Women's Economic Empowerment [PDF]

open access: yes, 2014
When women are economically empowered, communities and nations benefit. Yet, there has been a crucial knowledge gap regarding the most effective interventions that directly advance women's economic opportunities.
Mayra Buvinic, Rebecca Furst-Nichols
core  

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

open access: yesFEBS Letters, EarlyView.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard   +7 more
wiley   +1 more source

Research Integrity and Peer Review—past highlights and future directions

open access: yesResearch Integrity and Peer Review, 2018
In May 2016, we launched Research Integrity and Peer Review, an international, open access journal with fully open peer review (reviewers are identified on their reports and named reports are published alongside the article) to provide a home for ...
Stephanie L. Boughton   +4 more
doaj   +1 more source

Mapping the Empirical Evidence of the GDPR (In-)Effectiveness: A Systematic Review [PDF]

open access: yesarXiv, 2023
In the realm of data protection, a striking disconnect prevails between traditional domains of doctrinal, legal, theoretical, and policy-based inquiries and a burgeoning body of empirical evidence. Much of the scholarly and regulatory discourse remains entrenched in abstract legal principles or normative frameworks, leaving the empirical landscape ...
arxiv  

St. Serf's Church Tower, Dunning, Perthshire: Data Structure Report [PDF]

open access: yes, 2013
This report describes excavations undertaken as part of the SERF project. A small trench was excavated along the north wall of the tower of St Serf’s Church, Dunning.
Campbell, Ewan
core  

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

open access: yesFEBS Letters, EarlyView.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti   +2 more
wiley   +1 more source

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