Results 71 to 80 of about 1,700,151 (264)

Foundational Learning and Mental Health: Empirical Evidence from Botswana [PDF]

, 2023
Jennifer Opare-Kumi
openalex   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Developing an integrated depression and tuberculosis care pathway using a co-design approach in a low-resource setting

International Journal of Mental Health Systems
Background Evidence suggests the use of a participatory approach for the improvement of TB care, however, there is limited evidence on how integrated depression screening and care could be delivered with TB services.
Olamide Todowede, Zara Nisar, Saima Afaq, Sushama Kanan, Aliya Ayub, Rumana Huque, Akhtar Hussain, Mudasser Shehzad, Najma Siddiqi   +8 more
doaj   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

294 ACUPUNCTURE FOR OVERACTIVE BLADDER IN ADULTS: A COCHRANE REVIEW

Continence, 2022
E Hargreaves, Y Zhang, X Zhang, C Harding, K Baker, G Barry, N Kandala, C Clarkson   +7 more
doaj   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Effectiveness of an e-learning course in evidence-based medicine for foundation (internship) training [PDF]

, 2010
Julie Hadley, Regina Kulier, Javier Zamora, S.F.P.J. Coppus, Susanne Weinbrenner, Berrit Meyerrose, Tamás Decsi, Andrea R. Horvath, É. Nagy, José Ignacio Emparanza, Theodoros N. Arvanitis, Amanda Burls, Juan B Cabello, Marcin Kaczor, Gianni Zanrei, Karen Pierer, Regina Kunz, Veronica Wilkie, David Wall, Ben W. Mol, Khalid S. Khan   +20 more
openalex   +1 more source