Results 221 to 230 of about 10,003,521 (346)

Meta-Multimodal Foundation Models: A General Framework for Generating, Configuring, and Evolving Multimodal Model Mechanisms

Jincheng Zhang
openalex   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Towards generalisable foundation models for brain MRI. [PDF]

Npj Imaging
Mazher M, Parker GJM, Alexander DC.
europepmc   +1 more source

Evaluating the Robustness of Time-Series Foundation Models in Network Traffic Forecasting

Szabina Fodor, Zoltán Szabó
openalex   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

A benchmark study of vision and pathology foundation models for computational pathology. [PDF]

Nat Commun
Bareja R, Carrillo-Perez F, Zheng Y, Pizurica M, Nandi TN, Tian L, Shen J, Madduri R, Gevaert O.   +8 more
europepmc   +1 more source

A Survey on Side-Tuning for Foundation Models

Junchen Fu, Yu Ye, Xuri Ge, Yujie Jiang, Kaiwen Zheng, Wenhao Deng, Alexandros Karatzoglou, Ioannis Arapakis, Yongxin Ni, Joemon M. Jose, Xiawu Zheng, Zhumin Chen, Zhaochun Ren, Xiuzhen Cheng   +13 more
openalex   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Reliability of foundation models for image retrieval in histopathology. [PDF]

Npj Imaging
Shafique A, Qin X, Dy A, Alshamlan N, Androutsos D, Done SJ, Khademi A.   +6 more
europepmc   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source