Results 141 to 150 of about 7,389,079 (292)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Exam paper for second semester: Zulu for Foundation Phase ...
Mndawe, I.K., Dr., Madingiza, T.M., Mr.
core +1 more source
Evaluating the Foundation Phase\ud key findings on practitioner and\ud stakeholder views on the future\ud of the Foundation Phase [PDF]
The Foundation Phase (introduced\ud in 2008) provides a developmentally\ud appropriate experiential curriculum\ud for children aged 3-7 in Wales. The\ud Welsh Government commissioned\ud independent evaluation (led by\ud WISERD) aims to evaluate how well\ud it is being implemented, what\ud impact it has had, and ways in\ud which it can be improved.
Waldron, Samuel +2 more
openaire
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Al Mustafa Foundation of Utah flyer
Color image of Al Mustafa Foundation of Utah flyer. Email and website for the Al Mustafa Foundation.
Al Mustafa Foundation
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Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Exam paper for second semester: Zulu for Foundation Phase ...
University of Johannesburg
core +1 more source
Website for the Vietnam Education Foundation, established in 2000 to improve relations between the U.S. and Vietnam through educational exchange.
Vietnam Education Foundation (U.S.)
core

