Results 151 to 160 of about 915,687 (355)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Standards for Community Foundations: Challenges and Lessons Learned [PDF]

open access: yes, 2002
The purpose of this document is to share challenges and lessons learned related to developing and implementing a set of minimum operating standards for Michigan community foundations and their affiliates. Information presented in this article is based on
Karin E. Tice
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Installing SPSS 21 for Mac (STA10003 Foundations of Statistics)

open access: yes, 2012
This video shows you how to install SPSS 21 for Mac either via a disk or from a download from onthehub.com.
David Yammouni
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Objectivity in perspective: relationism in the interpretation of quantum mechanics

open access: yes, 2009
Pekka Lahti is a prominent exponent of the renaissance of foundational studies in quantum mechanics that has taken place during the last few decades.
Dennis Dieks   +4 more
core   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Physical and Philosophical Perspectives on Probability, Explanation and Time : (Workshop of the ESF Programme "The Philosophy of Science in a European Perspective", Utrecht University, 19-20 October 2009)

open access: yes, 2010
In 2008 the European Science Foundation Research Networking Programme ‘‘The Philosophy of Science in a European Perspective’’ (PSE) started its activities with a plenary conference in Vienna, in which the five PSE Research Teams met and where the ...
Dennis Dieks   +3 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

The Foundations of Institutional Economics

open access: yes, 2011
This book is about the foundations of institutional ...
Berger, Sebastian
core  

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