Results 141 to 150 of about 9,873,801 (377)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Breeding male mole-rats (Fukomys) use strong bites to defend reproductive monopoly
Communications BiologyBite force is a simple trait indicating an animal’s performance related to foraging, social dominance, and defence, all of which influence individual reproductive success.
Radim Šumbera +9 more
doaj +1 more source
A first estimation of chiral four-nucleon force effects in 4He [PDF]
, 2006 D. Rozpędzik +7 more
openalex +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Force Dependent Unbinding Kinetics of Actin Crosslinking Proteins Using a Four-Bead Optical Tweezers Assay [PDF]
, 2009 Melanie D. Reisinger, Matthias Rief
openalex +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Application of Upper Bound Analysis and Taguchi Method In Aluminium Extrusion
ABUAD Journal of Engineering Research and DevelopmentThis research explores the use of upper bound analysis in calculating the extrusion force through u-shaped dies with varying fillet radii, billet lengths, friction coefficients and billet temperatures.
Kamardeen Adebayo Ogunbajo +3 more
doaj +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source