Results 121 to 130 of about 4,474,733 (245)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Analysis on Variation of Groundwater Depth in Ningxia Yellow River Diversion Irrigation District Under Condition of Irrigation District Water-Saving

Renmin Zhujiang
As a vital irrigation oasis and national grain production base in the Yellow River Basin, the Ningxia Yellow River Diversion Irrigation District shoulders the dual missions of safeguarding regional food security and sustaining China's northwest ...
DUAN Chaoyu, CHENG Liang, FENG Zhimin
doaj  

Correction to: Rapid, midline retroperitoneal exposure for four-level anterior lumbar interbody fusion-technical case atlas. [PDF]

J Surg Case Rep, 2022
europepmc   +1 more source

Results of Four-Level Anterior Cervical Discectomy and Fusion Using Stand-Alone Interbody Titanium Cages. [PDF]

Asian Spine J, 2022
Alhashash M, Allouch H, Boehm H, Shousha M.   +3 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The effectiveness of dialectical behaviour therapy training: a quantitative systematic review using Kirkpatrick's four-level model. [PDF]

Borderline Personal Disord Emot Dysregul
Harris M, Lamers C, Swales M.
europepmc   +1 more source

Mapping between sound, brain and behaviour: four-level framework for understanding rhythm processing in humans and non-human primates. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2021
Lenc T, Merchant H, Keller PE, Honing H, Varlet M, Nozaradan S.   +5 more
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Development of a Panvascular Health Promotion and Risk Stratification Tool for Community Screening: Grounded in Four-Level Disease Prevention Theory. [PDF]

J Multidiscip Healthc
Su J, Yang Y, Chen B, Ding H, Wang X, Chen G, Wei Y, Wang D, Shen F, Shen Y.   +9 more
europepmc   +1 more source