AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Localizing of a Four-Level Atom via Absorption Spectrum [PDF]
Journal of Sciences, Islamic Republic of Iran, 2006 We propose a scheme for localizing an atom in a four-level configuration inside a classical standing wave field, conditioned upon the measurement of frequency of a weak probe field.
doaj
Rapid, midline retroperitoneal exposure for four-level anterior lumbar interbody fusion-technical case atlas. [PDF]
J Surg Case Rep, 2021 Falahee MH +5 more
europepmc +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Acute Changes in Interleukin-6 Level During Four Days of Long-Distance Walking
Journal of Inflammation Research, 2020 Viviane Soares,1 Ivan Silveira de Avelar,2 Patrícia Espíndola Mota Venâncio,1 Deise AA Pires-Oliveira,1 Pedro Henrique de Almeida Silva,1 Amanda Rodrigues Borges,1 Gustavo Paz Estevez Ferreira Fonseca,3 Matias Noll4 1Programa de P ...
Soares V +7 more
doaj
Evidence-Based Practice: Four Levels Revisited [PDF]
HERD: Health Environments Research & Design Journal, 2020 openaire +2 more sources
Individual, Maternal, Household, and Community Level Variability in Determining Inequalities in Childhood Anaemia within Ethiopia: Four-Level Multilevel Analysis Approach. [PDF]
Children (Basel), 2022 Kuse KA +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
BENZ WS: the Bologna ENZyme Web Server for four-level EC number annotation. [PDF]
Nucleic Acids Res, 2021 Baldazzi D +3 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source