Results 201 to 210 of about 4,474,733 (245)
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
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Four-Level Rectifier and Four-Level Inverter for Electric Drives
2006 8th International Conference on Actual Problems of Electronic Instrument Engineering, 2006A four-level three-phase diode clamped inverter fed by a correspondingly adapted untypical three-phase rectifier with two typical transformers is presented. The four-level rectifier is formed by consecutive connection of three rectifiers under the circuit of Scott for the bi-phase orthogonal voltage received from corresponding windings of two three ...
Nikolay Lopatkin +3 more
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Four-Level Cervical Corpectomy
Spine, 1998Retrospective analysis of 31 cases of cervical spondylotic myelopathy treated by four-level subaxial cervical corpectomy.To determine whether extremes of anterior decompression and fusion have inordinate or unique levels of morbidity.There is a paucity of data on experience with four-level corpectomy.
R L, Saunders, H J, Pikus, P, Ball
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Four-level refrigerator driven by photons
Physical Review E, 2015We propose a quantum absorption refrigerator driven by photons. The model uses a four-level system as its working substance and couples simultaneously to hot, cold, and solar heat reservoirs. Explicit expressions for the cooling power Q̇(c) and coefficient of performance (COP) η(COP) are derived, with the purpose of revealing and optimizing the ...
Jianhui, Wang +5 more
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Nursing Management (Springhouse), 1998
A clinical ladder identifies nursing competence, provides recognition and financial reward for bedside nursing practice, promotes responsibility, accountability, project and committee involvement, and enhances self-worth and positive morale. Because of the program's blend of skill levels, it develops a climate for clinical learning while promoting ...
openaire +2 more sources
A clinical ladder identifies nursing competence, provides recognition and financial reward for bedside nursing practice, promotes responsibility, accountability, project and committee involvement, and enhances self-worth and positive morale. Because of the program's blend of skill levels, it develops a climate for clinical learning while promoting ...
openaire +2 more sources
Audience Involvement in Advertising: Four Levels
Journal of Consumer Research, 1984The effectiveness of advertising messages is widely believed to be moderated by audience involvement. In this paper, psychological theories of attention and levels of processing are used to establish a framework that can accommodate the major consumer behavior theories of audience involvement.
Greenwald, Anthony G, Leavitt, Clark
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2014
This chapter is a brief description of the four levels in Chinese medicine, which chronicles the stages of symptoms as a pathogen penetrates levels of the body from the exterior to the interior. The first is the wei level, which corresponds to the taiyang stage, which describes the initial symptoms after a pathogenic invasion.
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This chapter is a brief description of the four levels in Chinese medicine, which chronicles the stages of symptoms as a pathogen penetrates levels of the body from the exterior to the interior. The first is the wei level, which corresponds to the taiyang stage, which describes the initial symptoms after a pathogenic invasion.
openaire +1 more source
Four levels of pattern recognition
Analytica Chimica Acta, 1978Abstract Problems of pattern recognition in chemistry and other subjects can be divided conveniently into four different types depending on the level of scope of the problem. (1) Classification into one of a number of defined classes. As an example blood samples taken from persons known to be either controls or welders are considered. The problem is
Christer Albano +6 more
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The Four Levels of Flow Control in SPIRO
1983The mechanisms for flow control for queued systems in the simulation package SPIRO are described. These can be regarded as consisting of four discrete levels: control of server networks, control of servers, control of stores, and interaction between tokens. Examples are given for each level.
Robert K. Bell, Pervez-Walter Ernest
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