Results 61 to 70 of about 4,379,102 (264)
The aim of an orthodontic treatment is to achieve aesthetic, dental health and the surrounding tissues, occlusal functional relationship, and stability.
Y. Yuliana +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Purpose: The study established the effect of resource orientation on service delivery of Level Four Public Hospitals in Kakamega County, Kenya Methodology/Approach: Mixed research design comprising of a descriptive and causal were applied.
Gregory Ombito +2 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Towards a quantum decision tree in a laser pumped four-level system
In this study, we examine an innovative framework towards implementing quantum decision trees utilizing a laser-driven four-level system. We discuss a diamond-shaped atomic configuration, in which we apply Lie-algebraic formalisms to analyze the dynamics
Dawit Hiluf Hailu
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Measuring training effectiveness of skill-based training in the industry sector
The purpose of this study was to evaluate the effectiveness of skill-based training courses in the industry sector according to Kirk Patrick model. Considered indexes in this evaluation were: rate of usage competencies, level of mastering in competencies,
Houman Dosti +2 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Four-Level Single-Stage Single-Source Boost-Inverter
This paper presents a novel concept of a DC-AC converter that ensures AC voltage modulation on four levels using a single branch and achieves voltage boosting.
Robert Stala +9 more
doaj +1 more source

