Results 121 to 130 of about 107,292 (309)
Advanced Science, EarlyView.This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu +20 more
wiley +1 more source
On Optimizing Steering Performance of Multi-axle Vehicle Based on Driving Force Control
MATEC Web of Conferences, 2017 The steering performance of multi-axle vehicle with independent driving system is affected by the distribution of the wheel driving force. A nonlinear vehicle dynamics model including magic formula tire model for describing 11 DoF four-axle vehicle with ...
Wu Zhicheng, Chen Cong
doaj +1 more source
Advanced Science, EarlyView.Resident myonuclei are the molecular “control centers” for large multinuclear muscle fibers. It is presumed that, with aging, these control centers become compromised and contribute to delayed or blunted muscle adaptive potential. This study is a detailed roadmap that exposes how young versus aged myonuclei respond to a hypertrophic loading stimulus ...
Pieter J. Koopmans +8 more
wiley +1 more source
Perception enhancement system for automotive steering [PDF]
, 2005 Laboratory-based experiments were conducted to evaluate the effect of the frequency and scale of transient vibration events on the human detection of road surface type by means of steering wheel vibration.
Berber-Solano, TP, Giacomin, J
core
Advanced Science, EarlyView.ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo +9 more
wiley +1 more source
A mobile planetary lander utilizing elastic loop suspension [PDF]
, 1976 Efforts to increase the cost effectiveness of future lunar and planetary rover missions have led to the mobile lander concept, which replaces the landing legs of a soft-lander craft with a compact mobility system of sufficient strength to withstand the ...
Trautwein, W.
core +1 more source
Advanced Science, EarlyView.This work demonstrates a receiver‐transmitter‐integrated metasurface that decomposes an incident wave into orthogonal components and routes them into separate channels. Inspired by a “Wheel‐of‐Fortune” mechanism, it enables independent control over the amplitude, phase, and polarization of the transmitted wave.
Tong Liu +8 more
wiley +1 more source
A state-of-the-art review on torque distribution strategies aimed at enhancing energy efficiency for fully electric vehicles with independently actuated drivetrains [PDF]
, 2019 © 2019, Levrotto and Bella. All rights reserved. Electric vehicles are the future of private passenger transportation. However, there are still several technological barriers that hinder the large scale adoption of electric vehicles. In particular, their
Lenzo, Basilio, Sforza, A, Timpone, F
core
Sulfide‐Based Electrolytes for All‐Solid‐State Sodium Batteries
Advanced Energy Materials, EarlyView.This review covers the structural features and synthesis strategies of sulfide‐based solid electrolytes, as well as critical challenges related to conductivity, interfacial and moisture stability, and scaling‐up for practical application in Sodium‐based All Solid‐State Batteries.
Han Yang +6 more
wiley +1 more source
Personnel emergency carrier vehicle [PDF]
, 1987 A personnel emergency carrier vehicle is disclosed which includes a vehicle frame supported on steerable front wheels and driven rear wheels. A supply of breathing air is connected to quick connect face mask coupling and umbilical cord couplings for ...
Fedor, Otto H., Owens, Lester J.
core +1 more source