Results 81 to 90 of about 4,114,452 (292)

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

Oscillation criteria for certain nonlinear fourth order equations

International Journal of Mathematics and Mathematical Sciences, 1983
This work investigates the behavior of solutions of certain nonlinear fourth order differential equations. An example is given showing that these equations can have both oscillatory and nonoscillatory solutions simultaneously.
W. E. Taylor
doaj   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Functional Model of Dissipative Fourth Order Differential Operators

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2013
In this paper, maximal dissipative fourth order operators with equal deficiency indices are investigated. We construct a self adjoint dilation of such operators.
Tuna Hüseyin
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Identifying High‐Impact Solutions to Address Racial and Ethnic Health Disparities in Lupus: A Consensus‐Based Approach

Arthritis Care &Research, EarlyView.
Objective We conducted formative research aimed at identifying solutions that address inequitable health outcomes in lupus due to adverse social determinants of health (SDoH). Methods We conducted a search for keywords, which provided insights into potential solutions and initiatives underway. An advisory panel of lupus experts iteratively reviewed the
Joy Buie, Michael P. Fisher, Kristen Backor, Hannah Tyldsley, Ashira Blazer, Candace Feldman, Andrea Knight, S. Sam Lim, Barbara Ann Polk, Ed Yelin, Edith Williams, Karen H. Costenbader   +11 more
wiley   +1 more source

Analytical and Solutions of Fourth Order Difference Equations

Communications in Advanced Mathematical Sciences, 2019
In this article, we presented the solutions of the following recursive sequences\[ x_{n+1}=\frac{x_{n-2}x_{n-3}}{x_{n}(\pm1\pm x_{n-2}x_{n-3})}, \] where the initial conditions $x_{-3}\ ,x_{-2}\ ,x_{-1}$\ and $x_{0}\ $are arbitrary real numbers. Also, we
Elsayed M. Elsayed, Marwa M. Alzubaidi
doaj   +1 more source

Fourth-order Elliptic Equations

Advanced Nonlinear Studies, 2014
Abstract We prove an existence result for a fourth order elliptic equation where the associated functional does not satisfy the Palais-Smale condition. We use some truncations argument and L∞-norm estimates.
openaire   +1 more source

Effect of Foot Orthoses on Midfoot Pain and the Volume of Bone Marrow Lesions in the Midfoot: A Randomized Mechanism of Action Study

Arthritis Care &Research, EarlyView.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain, and magnetic resonance imaging–confirmed midfoot BMLs ...
Jill Halstead, Anne‐Maree Keenan, Philip G. Conaghan, Dennis McGonagle, Anthony C. Redmond   +4 more
wiley   +1 more source

On a fourth order superlinear elliptic problem

Electronic Journal of Differential Equations, 2001
We prove the existence of a nonzero solution for the fourth order elliptic equation $$Delta^2u= mu u +a(x)g(u)$$ with boundary conditions $u=Delta u=0$. Here, $mu$ is a real parameter, $g$ is superlinear both at zero and infinity and $a(x)$ changes sign ...
M. Ramos, P. Rodrigues
doaj