Results 61 to 70 of about 10,993,960 (288)

Jumping nonlinearities for fourth order B.V.P. [PDF]

Annales de la Faculté des sciences de Toulouse : Mathématiques, 1993
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
García-Huidobro, Marta, Manásevich, Raúl   +1 more
openaire   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Oscillation of fourth-order quasilinear differential equations [PDF]

, 2015
summary:We study oscillatory behavior of a class of fourth-order quasilinear differential equations without imposing restrictive conditions on the deviated argument.
Zhang, Chenghui, Rogovchenko, Yuriy V., Li, Tongxing   +2 more
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Oscillation criteria for fourth order half-linear differential equations [PDF]

, 2011
summary:Criteria for oscillatory behavior of solutions of fourth order half-linear differential equations of the form \begin{equation*} \big (|y^{\prime \prime }|^\alpha {\rm sgn\ } y^{\prime \prime }\big )^{\prime \prime } + q(t)|y|^\alpha {\rm sgn}\ y =
Jaroš, Jaroslav, Tanigawa, Tomoyuki, Takaŝi, Kusano, Ken-ichi Kamo, Hiroyuki Usami   +4 more
core   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Quantifying and Counteracting the Impact of Erroneous and/or Incomplete Information via High-Order Predictive Modeling: Methodology and Illustrative Applications to Nuclear Reactor Models

Journal of Nuclear Engineering
This work highlights the major benefits of applying the “Fourth-Order Best-Estimate Predicted Results with Reduced Uncertainties Predictive Modeling” (4th-BERRU-PM) methodology to quantify and remedy the impact of possibly faulty computational or ...
Dan Gabriel Cacuci
doaj   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Existence of positive solutions for a fourth-order multi-point beam problem on measure chains

Electronic Journal of Differential Equations, 2009
This article concerns the fourth-order multi-point beam problem $$displaylines{ (EIW^{Delta abla }) ^{ abla Delta }(x)=m(x)f(x,W(x)),quad xin [x_{1},x_{n}]_{mathbb{X}} cr W( ho ^2(x_{1}))=sum_{i=2}^{n-1}a_iW(x_i),quad W^{Delta}( ho ^2(x_{1}))=0, cr
Douglas R. Anderson, Feliz Minhos
doaj