Results 41 to 50 of about 10,993,960 (288)
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Electronic Journal of Differential Equations, 2017 In this article, we give sufficient conditions for the boundedness, uniformly asymptotic stability and square integrability of the solutions to a fourth-order non-autonomous differential equation with bounded delay by using Lyapunov's second method.
Erdal Korkmaz, Cemil Tunc
doaj
Explicit Runge–Kutta–Nyström-Type Schemes for Fourth-Order Systems y(4)=f (x, y, y′)
AxiomsThis work addresses the numerical solution of fourth-order initial value problems of the form y(4)=f(x,y,y′), extending the capabilities of standard Runge–Kutta–Nyström (RKN) methods which are typically limited to y(4)=f(x,y). Problems of this type arise
Rubayyi T. Alqahtani +2 more
doaj +1 more source
Second order splitting for a class of fourth order equations [PDF]
Mathematics of Computation, 2019 We formulate a well-posedness and approximation theory for a class of generalised saddle point problems. In this way we develop an approach to a class of fourth order elliptic partial differential equations using the idea of splitting into coupled second order equations.
Charles M. Elliott +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Effective-fourth-order resonator based MASH bandpass sigma-delta modulators
, 1997 Two novel effective-fourth-order (eighth-order) resonator based MASH (MultistAge noise SHaping) bandpass Σ-Δ modulators are introduced at the behavioural level and subsequently examined by simulations utilising the ALTA SPW environment.
Morling, R.C.S., Kale, I., Al-Janabi, M.
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Horizon thermodynamics in fourth-order gravity
Physics Letters B, 2017 In the framework of horizon thermodynamics, the field equations of Einstein gravity and some other second-order gravities can be rewritten as the thermodynamic identity: dE=TdS−PdV.
Meng-Sen Ma
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
A fourth‐order incremental ADC in three‐step
The Journal of Engineering, 2021 This letter presents a second‐order incremental ADC (IADC) operated in three steps, which extends the performance of a second‐order IADC close to that of a fourth‐order IADC with only two amplifiers.
Jia‐Sheng Huang +5 more
doaj +1 more source