Results 71 to 80 of about 1,729,084 (328)

The Crescent Student Newspaper, October 5, 1995

open access: yes, 1995
Student newspaper of George Fox College (later George Fox University).
George Fox University Archives
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The Crescent Student Newspaper, April 9, 1993

open access: yes, 1993
Student newspaper of George Fox College (later George Fox University).
George Fox University Archives
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Early organization, commercialization and weaponization of social media in the entertainment industry: A case study, Bones, season 6 (2010–2011)

open access: yesCogent Social Sciences, 2017
As a television series, the Fox procedural crime drama Bones is exceptional. Having completed its twelfth and final season (2017), it is the longest running drama in the studio’s history.
Susan E. James
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The Crescent Student Newspaper, November 6, 1992

open access: yes, 1992
Student newspaper of George Fox College (later George Fox University).
George Fox University Archives
core   +2 more sources

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