Results 61 to 70 of about 23,538 (306)
Advanced Science, EarlyView.Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye +9 more
wiley +1 more source
Environmental drivers of rabies in the Volga region of Russia: application of the maxent model
Frontiers in Veterinary ScienceIntroductionUnderstanding the dynamics of rabies virus spread in wild populations is essential for experts working to developing strategies to that protect ecosystems and prevent conflicts between wild and domestic animals. This is particularly important
Olga I. Zakharova +6 more
doaj +1 more source
Law and Philosophy, 2015 Ronald Dworkin maintains that value is unitary, in the sense that different values do not conflict. This article resists this ‘hedgehog’ view with reference to the values of equality and utility. These appear to yield conflicting prescriptions in cases where one possible distribution gives different individuals the same amount of advantage, and the ...
openaire +1 more source
Advanced Science, EarlyView.Ubiquilin (UBQLN), like many other human proteins, contains both well‐folded and disordered regions. Here, we show that intramolecular interactions between disordered regions and folded domains modulate between open and closed topologies of UBQLN proteins, altering their structure and function.
Jessica K. Niblo +4 more
wiley +1 more source
Urban ScienceUrbanisation exerts profound effects on biodiversity, driving species extinctions while promoting behavioural adaptations in generalist taxa. The European badger (Meles meles) exemplifies such adaptability, exploiting anthropogenic resources and ...
Francesco Bisi +5 more
doaj +1 more source
Are foxes (Vulpes spp.) good sentinel species for Toxoplasma gondii in northern Canada?
Parasites & Vectors, 2022 Background In changing northern ecosystems, understanding the mechanisms of transmission of zoonotic pathogens, including the coccidian parasite Toxoplasma gondii, is essential to protect the health of vulnerable animals and humans.
Émilie Bouchard +14 more
doaj +1 more source
Foxes Fox and Freedom of the City 2005 [PDF]
, 2004 Ongoing collaboration with improvising musicians. Foxes Fox (69.28) and 'Freedom of the City’ (A 79.44, B 78.39) comprise two selected recordings with improvising musicians.
Beresford, S. +3 more
core
Neospora caninum and Toxoplasma gondii antibodies in red foxes ( Vulpes vulpes ) in the Czech Republic [PDF]
, 2015 [b]Introduction and objective.[/b] Neospora caninum and [i]Toxoplasma gondii [/i]are worldwide spread parasites, causing serious illnesses in sensitive animals; toxoplasmosis is also important zoonosis.
Bartova, E. +7 more
core +1 more source
Advanced Science, EarlyView.Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang +19 more
wiley +1 more source
The role of Grey-headed Flying-foxes in the ecology of Hendra virus, Menangle virus and Australian bat lyssavirus [PDF]
, 2002 Three previously unknown viruses have been recently described in flying-foxes. Hendra virus, Menangle virus and Australian bat lyssavirus (ABL) are regarded as emerging diseases of potential importance to both animal and public health.
Field, Hume, Hume Field
core +1 more source