Results 121 to 130 of about 7,684 (200)

Functional exploration of the adult ovarian granulosa cell tumor-associated somatic FOXL2 mutation p.Cys134Trp (c.402C>G).

PLoS ONE, 2010
BackgroundThe somatic mutation in the FOXL2 gene c.402C>G (p.Cys134Trp) has recently been identified in the vast majority of adult ovarian granulosa cell tumors (OGCTs) studied. In addition, this mutation seems to be specific to adult OGCTs and is likely
Bérénice A Benayoun, Sandrine Caburet, Aurélie Dipietromaria, Adrien Georges, Barbara D'Haene, P J Eswari Pandaranayaka, David L'Hôte, Anne-Laure Todeschini, Sankaran Krishnaswamy, Marc Fellous, Elfride De Baere, Reiner A Veitia   +11 more
doaj   +1 more source

Effects of an inhibitor of the gamma-secretase complex on proliferation and apoptotic parameters in a FOXL2-mutated granulosa tumor cell line (KGN). [PDF]

, 2013
Ovarian granulosa cell tumors (GCTs) represent 3%-5% of all ovarian malignancies. Treatments have limited proven efficacy and biologically targeted treatment is lacking.
Abramovich, Dalhia Nurit, de Zúñiga, Ignacio Javier, Irusta, Griselda, Parborell, Maria Fernanda Agustina, Pazos Maidana, María Camila, Tesone, Marta   +5 more
core   +2 more sources

Health and health care inequalities in Switzerland : a brief review of the literature [PDF]

, 2003
Through a review of the published literature on inequalities in health and health care in Switzerland, this paper covers major issues of inequality in health status, health care delivery, health care financing, and relationships between social inequality
Benkassmi, Mohamed, Holly, Alberto
core  

Characteristics and outcome of recurrence in molecularly defined adult-type ovarian granulosa cell tumors [PDF]

, 2016
Objective. Adult-type ovarian granulosa cell tumors (AGCTs) have an unpredictable tendency to relapse. In a carefully validated patient cohort, we evaluated the prognostic factors related to AGCT recurrence. Methods.
Bryk, Saara Susanna, Butzow, Ralf, Färkkilä, Anniina, Heikinheimo, Markku, Johanna, Tapper, Leminen, Arto, Riska, Annika, Unkila-Kallio, Leila   +7 more
core   +1 more source

RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2

Nature Communications, 2019
Proper ovarian differentiation requires RUNX1. Here, the authors show that double knockout of Runx1/Foxl2 results in masculinization of fetal ovaries, and that RUNX1 and FOXL2 jointly occupy common chromatin regions to maintain pre-granulosa cell ...
Barbara Nicol, Sara A. Grimm, Frédéric Chalmel, Estelle Lecluze, Maëlle Pannetier, Eric Pailhoux, Elodie Dupin-De-Beyssat, Yann Guiguen, Blanche Capel, Humphrey H.-C. Yao   +9 more
doaj   +1 more source

Differential expression and genetic polymorphism of DMRT1 and FOXL2 genes in the gonads of Kadaknath chicken

Indian Journal of Animal Sciences
In chicken, the left ovary is functional and the right ovary becomes rudimentary in the later stage of the embryonic development. The expression and genetic polymorphism of the DMRT1 and FOXL2 genes are assessed in order to understand the distinct ...
SHIVANI BACHAMOLLA, JAYAKUMAR SIVALINGAM, VELPULA CHINNIPREETAM, DAIDA KRISHNA, SHANMUGAM MURUGESAN, B RAJITH REDDY, TARUN KUMAR BHATTACHARYA, RAJKUMAR ULLENGALA   +7 more
doaj   +1 more source

FOXL2 mutations in Indian families with blepharophimosis-ptosis-epicanthus inversus syndrome [PDF]

, 2007
De Baere, Elfride, Jitendra, Jethani, Nallathambi, Jeyabalan, Neethirajan, Guruswamy, Sundaresan, Periasamy, Usha, Kim   +5 more
core   +2 more sources

Blepharophimosis-ptosis-epicanthus inversus syndrome in a Pakistani pedigree [PDF]

, 2010
Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) is a rare developmental ocular disorder. We report this condition affecting 4 members of a Pakistani family across three generations.
Ahmad, Khabir, Chaudhry, Tanveer Anjum, Khalid, Mirza Umair, Saleem, Taimur   +3 more
core   +1 more source

FOXL2 Gene [PDF]

, 2020
openaire   +1 more source

FOXL2 wt Allele [PDF]

, 2020
openaire   +1 more source