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miRNAs Regulate miRNAs: Coordinated Transcriptional and Post-Transcriptional Regulation [PDF]

Cell Cycle, 2006
microRNAs are short single-stranded RNA molecules that negatively regulate gene expression at post-transcriptional level. Recently it has been demonstrated that microRNAs are involved in many physiological processes, including differentiation and development.
Andrea Tuccoli, Laura Poliseno, Giuseppe Rainaldi   +2 more
openalex   +4 more sources

Transcriptional regulation [PDF]

EMBO reports, 2008
Overall, the meeting provided an excellent environment for those interested in transcriptional regulation to interact and to hear about a diverse array of topics, which stimulated lively discussions from the interdisciplinary audience. It was a consensus opinion that the meeting was a great success and it is hoped that the keystone symposia will ...
Jan Tuckermann, Peter Herrlich
  +6 more sources

Transcriptional regulation [PDF]

WormBook, 2005
The regulation of transcription in C. elegans shares many similarities to transcription in other organisms. The details of how specific transcription factors bind to target promoters and act as either activators or repressors are still being examined in many cases, but an increasing number of factors and their binding sites are being characterized ...
Peter G, Okkema, Michael, Krause
openaire   +4 more sources

The Roles of RUNX Proteins in Lymphocyte Function and Anti-Tumor Immunity

Cells, 2022
The Runt-related transcription factor (RUNX) family of proteins are crucial for many developmental and immuno-physiological processes. Their importance in cellular and tissue development has been repeatedly demonstrated as they are often found mutated ...
Wooseok Seo, Aneela Nomura, Ichiro Taniuchi   +2 more
doaj   +1 more source

Optical Clearing and Light Sheet Microscopy Imaging of Amphioxus

Frontiers in Cell and Developmental Biology, 2021
Cephalochordates (amphioxi or lancelets) are representatives of the most basally divergent group of the chordate phylum. Studies of amphioxus development and anatomy hence provide a key insight into vertebrate evolution.
Simona Machacova, Helena Chmelova, Anna Vavrova, Zbynek Kozmik, Iryna Kozmikova   +4 more
doaj   +1 more source

The role of input noise in transcriptional regulation [PDF]

, 2007
Even under constant external conditions, the expression levels of genes fluctuate. Much emphasis has been placed on the components of this noise that are due to randomness in transcription and translation; here we analyze the role of noise associated ...
A Bar–Even, AA Verveen, AA Verveen, AM Walczak, C Zhao, CF Stevens, DS Burz, E Ozbudak, E Schneidman, F Conti, FJ Sigworth, FJ Sigworth, Gašper Tkačik, H Lecar, H Lecar, HB Barlow, HB Barlow, HC Berg, I Golding, J Paulsson, J Reinitz, JM Pedraza, JM Raser, JR Newman, JS van Zon, M Ptashne, MB Elowitz, N Rosenfeld, P Fatt, P Fatt, PS Swain, PV Pedone, RL Winston, Rory Edward Morty, S Hecht, S Hooshangi, SE Luria, T Gregor, T Gregor, Thomas Gregor, W Bialek, W Bialek, W Bialek, W Bialek, William Bialek, WJ Blake, X Ma   +46 more
core   +14 more sources

Transcriptional regulation of haematopoietic transcription factors [PDF]

Stem Cell Research & Therapy, 2011
The control of differential gene expression is central to all metazoan biology. Haematopoiesis represents one of the best understood developmental systems where multipotent blood stem cells give rise to a range of phenotypically distinct mature cell types, all characterised by their own distinctive gene expression profiles.
Wilson, Nicola K, Calero-Nieto, Fernando J, Ferreira, Rita, Göttgens, Berthold   +3 more
openaire   +2 more sources

Impaired tissue homing by the Ikzf3N159S variant is mediated by interfering with Ikaros function

Frontiers in Immunology, 2023
AIOLOS, encoded by IKZF3, is a member of the IKZF family of proteins that plays an important role in regulating late B-cell differentiation. Human individuals heterozygous for the AIOLOS p.N160S variant displayed impaired humoral immune responses as well
Jingjie Chang, Motoi Yamashita, Motoi Yamashita, Aditya K. Padhi, Kam Y. J. Zhang, Ichiro Taniuchi   +5 more
doaj   +1 more source

Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance

Cells, 2023
Chromatin remodeling complexes are required for many distinct nuclear processes such as transcription, DNA replication, and DNA repair. However, the contribution of these complexes to the development of complex tissues within an organism is poorly ...
Andrea Kuzelova, Naoko Dupacova, Barbora Antosova, Sweetu Susan Sunny, Zbynek Kozmik, Jan Paces, Arthur I. Skoultchi, Tomas Stopka, Zbynek Kozmik   +8 more
doaj   +1 more source

Information on Transcriptional Regulation and Signal Transduction of _Escherichia coli_ K-12 Integrated in the Database RegulonDB. [PDF]

, 2010
Since its inception, RegulonDB ("http://regulondb.ccg.unam.mx/":http://regulondb.ccg.unam.mx/) has been a database that compiles information about the regulation of transcription initiation of _Escherichia coli_ K-12. However, we are aware that
Alberto Santos-Zavaleta, Alberto Santos-Zavaleta, Heladia Salgado, Hilda Solano, Julio Collado-Vides, Martin Peralta-Gil, Socorro Gama-Castro, Verena Weiss   +7 more
core   +5 more sources