Results 1 to 10 of about 5,997 (67)

Post-transcriptional regulation across human tissues.

open access: yesPLoS Computational Biology, 2017
Transcriptional and post-transcriptional regulation shape tissue-type-specific proteomes, but their relative contributions remain contested. Estimates of the factors determining protein levels in human tissues do not distinguish between (i) the factors ...
Alexander Franks   +2 more
doaj   +2 more sources

Transcriptional and Post-transcriptional Regulation of Lignin Biosynthesis Pathway Genes in Populus

open access: yesFrontiers in Plant Science, 2020
Lignin is a heterogeneous polymer of aromatic subunits derived from phenylalanine. It is polymerized in intimate proximity to the polysaccharide components in plant cell walls and provides additional rigidity and compressive strength for plants ...
Jin Zhang   +9 more
doaj   +3 more sources

Post-transcriptional regulation of the transcriptional apparatus in neuronal development

open access: yesFrontiers in Molecular Neuroscience
Post-transcriptional mechanisms, such as alternative splicing and polyadenylation, are recognized as critical regulatory processes that increase transcriptomic and proteomic diversity.
Mohammad Nazim
doaj   +3 more sources

Novel Insights into the Molecular Mechanisms Governing Embryonic Epicardium Formation

open access: yesJournal of Cardiovascular Development and Disease, 2023
The embryonic epicardium originates from the proepicardium, an extracardiac primordium constituted by a cluster of mesothelial cells. In early embryos, the embryonic epicardium is characterized by a squamous cell epithelium resting on the myocardium ...
Rita Carmona   +6 more
doaj   +1 more source

Transcriptional and Post-Transcriptional Regulation of Autophagy

open access: yesCells, 2022
Autophagy is a widely conserved process in eukaryotes that is involved in a series of physiological and pathological events, including development, immunity, neurodegenerative disease, and tumorigenesis.
Qiuqin Ma   +5 more
doaj   +1 more source

Post-transcriptional regulation of erythropoiesis

open access: yesBlood Science, 2023
Erythropoiesis is a complex, precise, and lifelong process that is essential for maintaining normal body functions. Its strict regulation is necessary to prevent a variety of blood diseases.
Yanan Li   +5 more
doaj   +1 more source

Prokineticin-Receptor Network: Mechanisms of Regulation

open access: yesLife, 2022
Prokineticins are a new class of chemokine-like peptides that bind their G protein-coupled receptors, PKR1 and PKR2, and promote chemotaxis and the production of pro-inflammatory cytokines following tissue injury or infection.
Roberta Lattanzi, Rossella Miele
doaj   +1 more source

A Quarter Century History of ATML1 Gene Research

open access: yesPlants, 2021
The cloning of the ATML1 gene, encoding an HD-ZIP class IV transcription factor, was first reported in 1996. Because ATML1 mRNA was preferentially detected in the shoot epidermis, cis-regulatory sequences of ATML1 have been used to drive gene expression ...
Hiroyuki Iida, Shinobu Takada
doaj   +1 more source

Designing Lentiviral Vectors for Gene Therapy of Genetic Diseases

open access: yesViruses, 2021
Lentiviral vectors are the most frequently used tool to stably transfer and express genes in the context of gene therapy for monogenic diseases. The vast majority of clinical applications involves an ex vivo modality whereby lentiviral vectors are used ...
Valentina Poletti, Fulvio Mavilio
doaj   +1 more source

Regulation of Doublesex1 Expression for Environmental Sex Determination in the Cladoceran Crustacean Daphnia

open access: yesFrontiers in Cell and Developmental Biology, 2022
The cladoceran crustacean Daphnia produces only females by parthenogenesis in a healthy population. However, in response to environmental declines such as crowding and lack of foods, it produces eggs destined to become males that are genetically ...
Yasuhiko Kato, Hajime Watanabe
doaj   +1 more source

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