Results 31 to 40 of about 7,761,523 (290)
Involvement of microRNA in Solid Cancer: Role and Regulatory Mechanisms
Biomedicines, 2021 MicroRNAs (miRNAs) function as the post-transcriptional factor that finetunes the gene expression by targeting to the specific candidate. Mis-regulated expression of miRNAs consequently disturbs gene expression profile, which serves as the pivotal ...
Ying-Chin Lin +4 more
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Target mRNA abundance dilutes microRNA and siRNA activity
Molecular Systems Biology, 2010 Post‐transcriptional regulation by microRNAs and siRNAs depends not only on characteristics of individual binding sites in target mRNA molecules, but also on system‐level properties such as overall molecular concentrations.
Aaron Arvey +4 more
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Post-transcriptional regulation in the developing embryo [PDF]
, 2019 Embryonic development is critically reliant on well-defined spatial and temporal patterns of gene expression. These patterns are often achieved through the regulation of gene expression at the mRNA level.
Fernandes, Sara Maria Ferreira
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Post-transcriptional regulation of proinflammatory proteins [PDF]
Journal of Leukocyte Biology, 2004 AbstractPost-transcriptional mechanisms play a critical role in regulating the expression of numerous proteins that promote inflammatory arthritis. The mRNAs encoding a subset of these proteins possess adenine/uridine-rich elements (AREs) in their 3′-untranslated regions that profoundly influence the rate at which mRNA is degraded and translated into ...
Paul, Anderson +3 more
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Functional Role of Non-Coding RNAs during Epithelial-To-Mesenchymal Transition
Non-Coding RNA, 2018 Epithelial-to-mesenchymal transition (EMT) is a key biological process involved in a multitude of developmental and pathological events. It is characterized by the progressive loss of cell-to-cell contacts and actin cytoskeletal rearrangements, leading ...
Almudena Expósito-Villén +2 more
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A Genome-Scale Atlas Reveals Complex Interplay of Transcription and Translation in an Archaeon
mSystems, 2023 The scale of post-transcriptional regulation and the implications of its interplay with other forms of regulation in environmental acclimation are underexplored for organisms of the domain Archaea.
Alan P. R. Lorenzetti +11 more
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Post‐transcriptional regulation of polycistronic
WIREs RNA, 2022 AbstractAn important proportion of microRNA (miRNA) genes tend to lie close to each other within animal genomes. Such genomic organization is generally referred to as miRNA clusters. Even though many miRNA clusters have been greatly studied, most attention has been usually focused on functional impacts of clustered miRNA co‐expression.
Vilimova, Monika, Pfeffer, Sébastien
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Transcription and post-transcriptional regulation of spermatogenesis [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2010 Spermatogenesis in mammals is achieved by multiple players that pursue a common goal of generating mature spermatozoa. The developmental processes acting on male germ cells that culminate in the production of the functional spermatozoa are regulated at both the transcription and post-transcriptional levels. This review addresses recent progress towards
Anilkumar, Bettegowda +1 more
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Influenza Virus Usurps an Interferon-Induced Translational Program to Promote Viral Replication
Proceedings, 2020 Hosts mount prudently tuned responses to viral infection in an attempt to block nearly every step of the replication cycle. Viruses must adapt to replicate in this hostile antiviral cellular state.
Mitchell P. Ledwith +11 more
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Correction to: Post-Transcriptional Gene Regulation [PDF]
, 2022 The book was inadvertently published with incorrect affiliation for the authors "Katherine B. Henke, Rachel M. Miller, Rachel A. Knoener, Mark Scalf, Michele Spiniello, and Lloyd M. Smith" in the contributors' list in FM and in the metadata of chapter 12.
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