Results 31 to 40 of about 492,739 (258)
Post-transcriptional control of fungal cell wall synthesis
The Cell Surface, 2022 Pathogenic fungi hide from their hosts by camouflage, obscuring immunogenic cell wall components such as beta-glucan with innocuous coverings such as mannoproteins and alpha-glucan that are less readily recognised by the host.
Rebecca A. Hall, Edward W.J. Wallace
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Post-transcriptional regulation of the pluripotent state [PDF]
Current Opinion in Genetics & Development, 2017 Pluripotency describes the developmental capacity to give rise to all cell types in the adult body. A comprehensive understanding of the molecular mechanisms that regulate pluripotency is important for both basic and translational research. While earlier studies mostly focused on signaling pathways, transcriptional regulation, and epigenetic ...
Qing, Chen, Guang, Hu
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BMC Plant Biology, 2021 Seed germination is the process through which a quiescent organ reactivates its metabolism culminating with the resumption cell divisions. It is usually the growth of a plant contained within a seed and results in the formation of a seedling.
Xiaofei Xue +10 more
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Biomolecules, 2015 DDX6 (p54/RCK) is a human RNA helicase with central roles in mRNA decay and translation repression. To help our understanding of how DDX6 performs these multiple functions, we conducted the first unbiased, large-scale study to map the DDX6-centric ...
Rebecca Bish +6 more
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A Genome-Scale Atlas Reveals Complex Interplay of Transcription and Translation in an Archaeon
mSystems, 2023 The scale of post-transcriptional regulation and the implications of its interplay with other forms of regulation in environmental acclimation are underexplored for organisms of the domain Archaea.
Alan P. R. Lorenzetti +11 more
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Are microRNAs Important Players in HIV-1 Infection? An Update
Viruses, 2018 HIV-1 has already claimed over 35 million human lives globally. No curative treatments are currently available, and the only treatment option for over 36 million people currently living with HIV/AIDS are antiretroviral drugs that disrupt the function of ...
Muthukumar Balasubramaniam +2 more
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Involvement of microRNA in Solid Cancer: Role and Regulatory Mechanisms
Biomedicines, 2021 MicroRNAs (miRNAs) function as the post-transcriptional factor that finetunes the gene expression by targeting to the specific candidate. Mis-regulated expression of miRNAs consequently disturbs gene expression profile, which serves as the pivotal ...
Ying-Chin Lin +4 more
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Post-transcriptional regulation in metabolic diseases [PDF]
RNA Biology, 2012 Post-transcriptional gene regulation by microRNAs (miRNAs) and RNA-binding proteins (RBPs) is central to many biological functions. Aberrant gene expression patterns underlie many metabolic diseases that represent major public health concerns and formidable therapeutic challenges.
Wook, Kim, Eun, Kyung Lee
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Post-transcriptional regulation of microRNA expression [PDF]
RNA, 2006 microRNAs (miRNAs) are endogenous, noncoding ∼22-nucleotide RNA molecules that have recently emerged as fundamental, post-transcriptional regulators of cognate target gene expression. Many mammalian miRNAs are expressed in a tissue-specific manner, a phenomenon that has so far been attributed to transcriptional regulation.
Gregor, Obernosterer +3 more
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Target mRNA abundance dilutes microRNA and siRNA activity
Molecular Systems Biology, 2010 Post‐transcriptional regulation by microRNAs and siRNAs depends not only on characteristics of individual binding sites in target mRNA molecules, but also on system‐level properties such as overall molecular concentrations.
Aaron Arvey +4 more
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