CRP-cAMP mediates silencing of Salmonella virulence at the post-transcriptional level [PDF]
, 2018 Invasion of epithelial cells by Salmonella enterica requires expression of genes located in the pathogenicity island I (SPI-1). The expression of SPI-1 genes is very tightly regulated and activated only under specific conditions.
Balsalobre, Carlos +6 more
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Functional Characteristics of Gene Expression Motifs with Single and Dual Strategies of Regulation
, 2016 Transcriptional regulation by transcription factors and post-transcriptional regulation by microRNAs constitute two major modes of regulation of gene expression.
Bose, Indrani +2 more
core +1 more source
Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway. [PDF]
, 2017 Recent studies have linked branched-chain amino acid (BCAA) with numerous metabolic diseases. However, the molecular basis of BCAA's roles in metabolic regulation remains to be established.
Dong, Weibing +5 more
core +2 more sources
Post-Transcriptional Regulation of Chloramphenicol Acetyl Transferase [PDF]
Journal of Bacteriology, 1984 The +1 site for initiation of inducible chloramphenicol acetyl transferase (CAT) mRNA encoded by plasmid pC194 was determined experimentally by using [alpha-32P]ATP-labeled runoff transcripts partially digested with T1 RNase. By partial digestion of the in vitro transcripts with S1, T1, and cobra venom nucleases as probes of mRNA conformation, single ...
W H, Byeon, B, Weisblum
openaire +3 more sources
Influenza Virus Usurps an Interferon-Induced Translational Program to Promote Viral Replication
Proceedings, 2020 Hosts mount prudently tuned responses to viral infection in an attempt to block nearly every step of the replication cycle. Viruses must adapt to replicate in this hostile antiviral cellular state.
Mitchell P. Ledwith +11 more
doaj +1 more source
The Distinctive Regulation of Cyanobacterial Glutamine Synthetase [PDF]
, 2018 Glutamine synthetase (GS) features prominently in bacterial nitrogen assimilation as it catalyzes the entry of bioavailable nitrogen in form of ammonium into cellular metabolism. The classic example, the comprehensively characterized GS of enterobacteria,
Bolay, Paul +3 more
core +1 more source
miRNAs Regulate miRNAs: Coordinated Transcriptional and Post-Transcriptional Regulation [PDF]
Cell Cycle, 2006 microRNAs are short single-stranded RNA molecules that negatively regulate gene expression at post-transcriptional level. Recently it has been demonstrated that microRNAs are involved in many physiological processes, including differentiation and development.
Tuccoli A, Poliseno L, Rainaldi G
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Origins of Binary Gene Expression in Post-transcriptional Regulation by MicroRNAs
, 2012 MicroRNA-mediated regulation of gene expression is characterised by some distinctive features that set it apart from unregulated and transcription factor-regulated gene expression. Recently, a mathematical model has been proposed to describe the dynamics
Bose, Indrani, Ghosh, Sayantari
core +1 more source
Post-Transcriptional Regulation of Nutrient Transporters [PDF]
Plant Physiology, 2020 Most protein-coding genes in eukaryotes contain introns, and splicing of precursor mRNA (premRNA) is an essential step in gene expression. This posttranscriptional step of gene regulation takes place in the nucleus, is highly conserved among eukaryotes, and involves the coordinated and ...
openaire +2 more sources
Post-translational regulation of Oct4 transcriptional activity.
PLoS ONE, 2009 Oct4 is a key component of the molecular circuitry which regulates embryonic stem cell proliferation and differentiation. It is essential for maintenance of undifferentiated, pluripotent cell populations, and accomplishes these tasks by binding DNA in ...
Jonathan P Saxe +4 more
doaj +1 more source