Results 41 to 50 of about 7,761,523 (290)
Post-transcriptional regulation: The dawn of PTB [PDF]
Current Biology, 1997 The 'polypyrimidine-tract-binding protein' (PTB) participates in the control of alternative processing and translation of various RNAs, and may operate as a multifunctional regulator of tissue-specific gene expression.
Valcárcel, Juan, Gebauer, Fátima
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Post-Transcriptional and Epigenetic Regulation of Estrogen Signaling
The Journal of Pharmacology and Experimental Therapeutics, 2023 Post-translational and epigenetic regulation are important mechanisms controlling functions of genes and proteins. Although the "classic" estrogen receptors (ERs) have been acknowledged to function in mediating estrogen effects via transcriptional mechanisms, estrogenic agents modulate the turnover of several proteins via post-transcriptional and post ...
Cignarella A. +4 more
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Post-translational regulation of Oct4 transcriptional activity.
PLoS ONE, 2009 Oct4 is a key component of the molecular circuitry which regulates embryonic stem cell proliferation and differentiation. It is essential for maintenance of undifferentiated, pluripotent cell populations, and accomplishes these tasks by binding DNA in ...
Jonathan P Saxe +4 more
doaj +1 more source
, 2021 Our core timekeeping mechanism, the circadian clock, plays a vital role in immunity. Although the mechanics of circadian control over the immune response is generally explained by transcriptional activation or repression derived from this clock's ...
Jennifer M Hurley (9260246) +5 more
core +1 more source
Post-Transcriptional Regulation of Nutrient Transporters [PDF]
Plant Physiology, 2020 Most protein-coding genes in eukaryotes contain introns, and splicing of precursor mRNA (premRNA) is an essential step in gene expression. This posttranscriptional step of gene regulation takes place in the nucleus, is highly conserved among eukaryotes, and involves the coordinated and ...
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
Post-Transcriptional Regulation of Chloramphenicol Acetyl Transferase [PDF]
Journal of Bacteriology, 1984 The +1 site for initiation of inducible chloramphenicol acetyl transferase (CAT) mRNA encoded by plasmid pC194 was determined experimentally by using [alpha-32P]ATP-labeled runoff transcripts partially digested with T1 RNase. By partial digestion of the in vitro transcripts with S1, T1, and cobra venom nucleases as probes of mRNA conformation, single ...
W H, Byeon, B, Weisblum
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
, 2021 All code and data used in the manuscript "Kinetic modeling reveals additional regulation at co-transcriptional level by post-transcriptional sRNA ...
Reyer, M (via Mendeley Data) +1 more
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source