Results 1 to 10 of about 11,016 (219)
Systematic analysis of JmjC gene family and stress-response expression of KDM5 subfamily genes in Brassica napus [PDF]
PeerJ, 2021 Background Jumonji C (JmjC) proteins exert critical roles in plant development and stress response through the removal of lysine methylation from histones.
Xinghui He +5 more
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Epigenetic Regulation and Measurement of Epigenetic Changes [PDF]
Biological Research For Nursing, 2012 Epigenetic mechanisms provide an adaptive layer of control in the regulation of gene expression that enables an organism to adjust to a changing environment. Epigenetic regulation increases the functional complexity of deoxyribonucleic acid (DNA) by altering chromatin structure, nuclear organization, and transcript stability.
Stephens, Kimberly E +4 more
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Epigenetic regulation of myogenesis [PDF]
Epigenetics, 2009 Adult skeletal muscle provides a unique paradigm for studying stem to differentiated cell transitions. In response to environmental stress, quiescent muscle stem cells (satellite cells) are activated and proliferative, at which stage they can either differentiate and fuse to form new muscle fibers or alternatively self-renew and maintain the muscle ...
Eusebio, Perdiguero +3 more
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Metabolic Regulation of Epigenetics [PDF]
Cell Metabolism, 2012 How cells sense and respond to environmental cues remains a central question of biological research. Recent evidence suggests that DNA transcription is regulated by chromatin organization. However, the mechanism for relaying the cytoplasmic signaling to chromatin remodeling remains incompletely understood.
Lu, Chao, Thompson, Craig B.
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Telomerase Regulation: A Role for Epigenetics [PDF]
Cancers, 2021 Telomerase was first described by Greider and Blackburn in 1984, a discovery ultimately recognized by the Nobel Prize committee in 2009. The three decades following on from its discovery have been accompanied by an increased understanding of the fundamental mechanisms of telomerase activity, and its role in telomere biology.
Fatma Dogan, Nicholas R. Forsyth
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Cells, 2020 Chromosomes are organized into 3D structures that are important for the regulation of gene expression and differentiation. Important role in formation of inter-chromosome contacts play rDNA clusters that make up nucleoli. In the course of differentiation,
Nickolai A. Tchurikov +7 more
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Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals
Genome Biology, 2021 Background Precise gene dosage of the X chromosomes is critical for normal development and cellular function. In mice, XX female somatic cells show transcriptional X chromosome upregulation of their single active X chromosome, while the other X ...
Irene Talon +13 more
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Epigenetic regulation in medulloblastoma [PDF]
Molecular and Cellular Neuroscience, 2018 Medulloblastoma is the most common malignant childhood brain tumor. The heterogeneous tumors are classified into four subgroups based on transcription profiles. Recent developments in genome-wide sequencing techniques have rapidly advanced the understanding of these tumors.
Jiaqing, Yi, Jiang, Wu
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Nature Communications, 2023 Glioblastoma (GBM) ranks among the most lethal of human cancers, containing glioma stem cells (GSCs) that display therapeutic resistance. Here, we report that the lncRNA INHEG is highly expressed in GSCs compared to differentiated glioma cells (DGCs) and
Lihui Liu +20 more
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Lipid droplets are formed in 2-cell-like cells
The Journal of Reproduction and Development, 2021 Embryonic stem (ES) cells, derived from the inner cell mass of a blastocyst, are believed to pluripotent cells and give rise to embryonic, but not extraembryonic, tissues.
Asuka FURUTA, Toshinobu NAKAMURA
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