Results 31 to 40 of about 2,250,202 (262)
Epigenetic Regulation of Cellular Senescence [PDF]
Cells, 2022 Senescence is a complex cellular stress response that abolishes proliferative capacity and generates a unique secretory pattern that is implicated in organismal aging and age-related disease. How a cell transitions to a senescent state is multifactorial and often requires transcriptional regulation of multiple genes.
Jack Crouch +4 more
openaire +3 more sources
Epigenetic regulation of autophagy: A key modification in cancer cells and cancer stem cells. [PDF]
, 2021 Aberrant epigenetic alterations play a decisive role in cancer initiation and propagation via the regulation of key tumor suppressor genes and oncogenes or by modulation of essential signaling pathways.
Radpour, Ramin +2 more
core +2 more sources
Epigenetic Regulation in the Control of Flowering [PDF]
Cold Spring Harbor Symposia on Quantitative Biology, 2004 The timing of flowering has significant consequencesfor the reproductive success of plants. Plants need togauge when both environmental and endogenous cues areoptimal before undergoing the switch from vegetative toreproductive development. To achieve this, a complexregulatory network has evolved consisting of multiplepathways that quantitatively ...
Mylne, J. S. +3 more
openaire +4 more sources
Learning epigenetic regulation from mycobacteria [PDF]
, 2016 In a eukaryotic cell, the transcriptional fate of a gene is determined by the profile of the epigenetic modifications it is associated with and the conformation it adopts within the chromatin.
Khosla, Sanjeev +5 more
core +1 more source
Epigenetic regulation of cholesterol homeostasis [PDF]
Frontiers in Genetics, 2014 Although best known as a risk factor for cardiovascular disease, cholesterol is a vital component of all mammalian cells. In addition to key structural roles, cholesterol is a vital biochemical precursor for numerous biologically important compounds including oxysterols and bile acids, as well as acting as an activator of critical morphogenic systems ...
Steve eMeaney, Steve eMeaney
openaire +4 more sources
Asymmetric division of stem cells and its cancer relevance
Cell RegenerationAsymmetric division is a fundamental process for generating cell diversity and maintaining the stem cell population. During asymmetric division, proteins, organelles, and even RNA are distributed unequally between the two daughter cells, determining ...
Shanshan Chao, Huiwen Yan, Pengcheng Bu
doaj +1 more source
Clinical analysis of 11 cases of nocardiosis
Open Medicine, 2021 Nocardiosis is a rare, life-threatening, opportunistic, and suppurative infection. Its clinical manifestation lacks specificity, which makes early diagnosis difficult.
Li Yiqing +7 more
doaj +1 more source
Epigenetic regulation in chondrogenesis.
Acta medica Okayama, 2010 Epigenetics is an essential mechanism to control gene expression and fundamental cellular processes. DNA methylation in CpG-rich promoters correlates with gene silencing. Histone modification including histone acetylation and deacetylation determines the stability of the chromatin structure.
Furumatsu, Takayuki, Ozaki, Toshifumi
openaire +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source