Epigenetic aberrations and cancer [PDF]
, 2006 The correlation between epigenetic aberrations and disease underscores the importance of epigenetic mechanisms.
Ducasse, Miryam +3 more
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Novel insights into the epigenetic regulation of Plasmodium falciparum virulence genes [PDF]
, 2013 Plasmodium falciparum malaria still places a major health burden upon the developing world. The high virulence of this parasite is linked to the variegated expression of single P.
Brancucci, Nicolas Michel Beat
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Epigenetic Mechanisms of Inflammasome Regulation [PDF]
International Journal of Molecular Sciences, 2020 The innate immune system represents the host’s first-line defense against pathogens, dead cells or environmental factors. One of the most important inflammatory pathways is represented by the activation of the NOD-like receptor (NLR) protein family. Some NLRs induce the assembly of large caspase-1-activating complexes called inflammasomes.
Poli G. +6 more
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Role of histone methylation in paternal transmission of epigenetic information [PDF]
, 2010 During the development of multi-cellular organisms, one genome gives rise to multiple differentiated cell types. This is achieved by sequence specific transcription factors and different epigenetic mechanisms, which collaborate in reading the genetic ...
Brykczynska, Urszula
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Epigenetic regulation of myogenesis [PDF]
Epigenetics, 2009 Adult skeletal muscle provides a unique paradigm for studying stem to differentiated cell transitions. In response to environmental stress, quiescent muscle stem cells (satellite cells) are activated and proliferative, at which stage they can either differentiate and fuse to form new muscle fibers or alternatively self-renew and maintain the muscle ...
Eusebio, Perdiguero +3 more
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Oxidative stress and epigenetic regulation in ageing and age-related diseases [PDF]
, 2013 Recent statistics indicate that the human population is ageing rapidly. Healthy, but also diseased, elderly people are increasing. This trend is particularly evident in Western countries, where healthier living conditions and better cures are available ...
Francesco Spallotta +13 more
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Epigenetic-based therapies for Friedreich ataxia [PDF]
, 2014 This article has been made available through the Brunel Open Access Publishing Fund.Friedreich ataxia (FRDA) is a lethal autosomal recessive neurodegenerative disorder caused primarily by a homozygous GAA repeat expansion mutation within the first intron
Madhavi Sandi +14 more
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Peptidylarginine Deiminase (PAD) and Post-Translational Protein Deimination—Novel Insights into Alveolata Metabolism, Epigenetic Regulation and Host–Pathogen Interactions [PDF]
, 2021 The alveolates (Superphylum Alveolata) comprise a group of primarily single-celled eukaryotes that have adopted extremely diverse modes of nutrition, such as predation, photoautotrophy and parasitism.
Lange, S. +2 more
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The nuclear pore complex : its role in chromatin structure and RNA export [PDF]
, 2015 Epigenetic regulation of gene expression is a relatively new and rapidly developing research field. It studies the mechanisms of regulation of gene expression, which although heritable, occur independently of changes in the DNA sequence and certainly aid
Hristova, Emilia
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How might epigenetics contribute to ecological speciation? [PDF]
, 2013 Speciation research has seen a renewed interest in ecological speciation, which emphasises divergent ecological selection leading to the evolution of reproductive isolation.
Ritchie, Michael G., Smith, Gilbert
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