Results 11 to 20 of about 2,689,531 (302)
Epigenetic Regulation of Adipokines [PDF]
International Journal of Molecular Sciences, 2017 Adipose tissue expansion in obesity leads to changes in the expression of adipokines, adipocyte-specific hormones that can regulate whole body energy metabolism. Epigenetic regulation of gene expression is a mechanism by which cells can alter gene expression through the modifications of DNA and histones.
Pham, Tho X., Lee, Ji-Young
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Epigenetic Regulation and Measurement of Epigenetic Changes [PDF]
Biological Research For Nursing, 2012 Epigenetic mechanisms provide an adaptive layer of control in the regulation of gene expression that enables an organism to adjust to a changing environment. Epigenetic regulation increases the functional complexity of deoxyribonucleic acid (DNA) by altering chromatin structure, nuclear organization, and transcript stability.
Stephens, Kimberly E +4 more
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Epigenetic Regulation of Cellular Senescence [PDF]
Cells, 2022 Senescence is a complex cellular stress response that abolishes proliferative capacity and generates a unique secretory pattern that is implicated in organismal aging and age-related disease. How a cell transitions to a senescent state is multifactorial and often requires transcriptional regulation of multiple genes.
Jack Crouch +4 more
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Epigenetic regulation of oxysterol formation [PDF]
Biochimie, 2013 Oxysterols are oxygenated derivatives of cholesterol that may be formed by either enzymatic or non-enzymatic mechanisms. Expression of the genes responsible for oxysterol synthesis (GROS) is known to be restricted across different tissues and cell types.
Meaney, Steve
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The Epigenetic Regulation of Wound Healing [PDF]
Advances in Wound Care, 2014 Significance: Epigenetic regulatory mechanisms are essential for epidermal homeostasis and contribute to the pathogenesis of many skin diseases, including skin cancer and psoriasis. However, while the epigenetic regulation of epidermal homeostasis is now becoming active area of research, the epigenetic mechanisms controlling the wound healing response ...
Lewis, Christopher J. +4 more
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Epigenetic regulation in medulloblastoma [PDF]
Molecular and Cellular Neuroscience, 2018 Medulloblastoma is the most common malignant childhood brain tumor. The heterogeneous tumors are classified into four subgroups based on transcription profiles. Recent developments in genome-wide sequencing techniques have rapidly advanced the understanding of these tumors.
Jiaqing, Yi, Jiang, Wu
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Metabolic Regulation of Epigenetics [PDF]
Cell Metabolism, 2012 How cells sense and respond to environmental cues remains a central question of biological research. Recent evidence suggests that DNA transcription is regulated by chromatin organization. However, the mechanism for relaying the cytoplasmic signaling to chromatin remodeling remains incompletely understood.
Lu, Chao, Thompson, Craig B.
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Epigenetic Regulation in Plants [PDF]
Cold Spring Harbor Perspectives in Biology, 2014 The study of epigenetics in plants has a long and rich history, from initial descriptions of non-Mendelian gene behaviors to seminal discoveries of chromatin-modifying proteins and RNAs that mediate gene silencing in most eukaryotes, including humans. Genetic screens in the model plant Arabidopsis have been particularly rewarding, identifying more than
Craig S, Pikaard +1 more
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Telomerase Regulation: A Role for Epigenetics [PDF]
Cancers, 2021 Telomerase was first described by Greider and Blackburn in 1984, a discovery ultimately recognized by the Nobel Prize committee in 2009. The three decades following on from its discovery have been accompanied by an increased understanding of the fundamental mechanisms of telomerase activity, and its role in telomere biology.
Fatma Dogan, Nicholas R. Forsyth
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Epigenetic regulation during fetal femur development: DNA methylation matters [PDF]
, 2013 Epigenetic modifications are heritable changes in gene expression without changes in DNA sequence. DNA methylation has been implicated in the control of several cellular processes including differentiation, gene regulation, development, genomic ...
Oreffo Richard O. C. +26 more
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