Results 11 to 20 of about 2,250,202 (262)

Epigenetic Regulation and Measurement of Epigenetic Changes [PDF]

Biological Research For Nursing, 2012
Epigenetic mechanisms provide an adaptive layer of control in the regulation of gene expression that enables an organism to adjust to a changing environment. Epigenetic regulation increases the functional complexity of deoxyribonucleic acid (DNA) by altering chromatin structure, nuclear organization, and transcript stability.
Stephens, Kimberly E, Miaskowski, Christine A, Levine, Jon D, Pullinger, Clive R, Aouizerat, Bradley E   +4 more
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Epigenetic Regulation of Adipokines [PDF]

International Journal of Molecular Sciences, 2017
Adipose tissue expansion in obesity leads to changes in the expression of adipokines, adipocyte-specific hormones that can regulate whole body energy metabolism. Epigenetic regulation of gene expression is a mechanism by which cells can alter gene expression through the modifications of DNA and histones.
Pham, Tho X., Lee, Ji-Young
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Epigenetic regulation in medulloblastoma [PDF]

Molecular and Cellular Neuroscience, 2018
Medulloblastoma is the most common malignant childhood brain tumor. The heterogeneous tumors are classified into four subgroups based on transcription profiles. Recent developments in genome-wide sequencing techniques have rapidly advanced the understanding of these tumors.
Jiaqing, Yi, Jiang, Wu
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Metabolic Regulation of Epigenetics [PDF]

Cell Metabolism, 2012
How cells sense and respond to environmental cues remains a central question of biological research. Recent evidence suggests that DNA transcription is regulated by chromatin organization. However, the mechanism for relaying the cytoplasmic signaling to chromatin remodeling remains incompletely understood.
Lu, Chao, Thompson, Craig B.
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Epigenetic Regulation in Plants [PDF]

Cold Spring Harbor Perspectives in Biology, 2014
The study of epigenetics in plants has a long and rich history, from initial descriptions of non-Mendelian gene behaviors to seminal discoveries of chromatin-modifying proteins and RNAs that mediate gene silencing in most eukaryotes, including humans. Genetic screens in the model plant Arabidopsis have been particularly rewarding, identifying more than
Craig S, Pikaard, Ortrun, Mittelsten Scheid   +1 more
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Telomerase Regulation: A Role for Epigenetics [PDF]

Cancers, 2021
Telomerase was first described by Greider and Blackburn in 1984, a discovery ultimately recognized by the Nobel Prize committee in 2009. The three decades following on from its discovery have been accompanied by an increased understanding of the fundamental mechanisms of telomerase activity, and its role in telomere biology.
Fatma Dogan, Nicholas R. Forsyth
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Epigenetic regulation during fetal femur development: DNA methylation matters [PDF]

, 2013
Epigenetic modifications are heritable changes in gene expression without changes in DNA sequence. DNA methylation has been implicated in the control of several cellular processes including differentiation, gene regulation, development, genomic ...
Oreffo Richard O. C., Oreffo, Richard O. C., Antonio Gonzalez, González Martínez-Pedrayo, Antonio, Imagawa, K., Richard O C Oreffo, de Andrés María C., Gonzalez, A., Roach Helmtrud I., Wilson, David I., Kingham, Emmajayne, Oreffo, R.O., Kingham Emmajayne, Helmtrud I Roach, Oreffo, Richard O C, Gomez-Reino, J.J., Emmajayne Kingham, Kei Imagawa, María C de Andrés, Wilson, D.I., Roach, Helmtrud I, Wilson David I., de Andrés, María C., Imagawa, Kei, Roach, Helmtrud I., De Andrés González, Mª Carmen, Imagawa Kei, Wilson, David I, Neves, Nuno M., David I Wilson, Gonzalez, Antonio, Roach, H.I., Kingham, E., Gonzalez Antonio, de Andrés, M.C.   +34 more
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Sirtuins in Epigenetic Regulation [PDF]

Chemical Reviews, 2015
1.1. Discovery of Sirtuins The founding member of sirtuin is the yeast-silencing information regulator 2 (SIR2) protein, one of four proteins (SIR1–4) required for silencing the mating-type information loci in yeast.1 SIR2–4, but not SIR1, are also required for gene silencing at telomeres.2 SIR2 also mediates gene silencing at the rDNA (rDNA) loci ...
Jing, Hui, Lin, Hening
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Epigenetic regulation of adaptive responses of forest tree species to the environment [PDF]

, 2013
Epigenetic variation is likely to contribute to the phenotypic plasticity and adaptative capacity of plant species, and may be especially important for long-lived organisms with complex life cycles, including forest trees.
Maury, Stéphane, Bräutigam, Katharina, Antje Rohde, M. Ángeles Guevara, Dolores Abarca, Rohde, Antje, Fluch, S., Fluch, Silvia, Fraga, Mario F., Clément Lafon‐Placette, Johnsen, Oystein, Lafon-Placette, Clément, Jose, Gutiérrez-Marcos, Angeles Guevara, M., Campbell, Malcolm M., Fossdal, Carl G., Steven H. Strauss, Bräutigam, K., Fossdal, C. G., Abarca, Dolores, Mirouze, M., Katharina Bräutigam, Malcolm M. Campbell, Lafon-Placette, C., Vining, Kelly J., Gutierrez Marcos, Jose, Campbell, M. M., Rohde, A., Fernandez Fraga, Mario, José Gutiérrez Marcos, Marcos, J. G., Marie Mirouze, Silvia Fluch, Fraga, Mario Fernández, Cervera, María-Teresa, Díaz-Sala, Carmen, María‐Teresa Cervera, Guevara, M. Ángeles, Cervera, María Teresa, Johnsen, Øystein, Strauss, Steven H., Mario Fernández Fraga, Braeutigam, Katharina, Guevara, M Ángeles, Øystein Johnsen, Stéphane Maury, Mirouze, Marie, Kelly J. Vining, Johnsen, O., Vining, K. J., Carl G. Fossdal, Carmen Díaz‐Sala   +51 more
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Epigenetic regulation of hematopoiesis [PDF]

International Journal of Hematology, 2012
Epigenetic regulation is required not only for development, but also for tissue homeostasis, which is maintained via the self-renewal and differentiation of somatic stem cells. Accumulating evidence suggests that epigenetic regulators play critical roles in the maintenance of both self-renewing hematopoietic stem cells and leukemic stem cells.
Goro, Sashida, Atsushi, Iwama
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