Results 11 to 20 of about 3,231,478 (258)

Modelling transcriptional regulation with a mixture of factor analyzers and variational Bayesian expectation maximization [PDF]

, 2009
Understanding the mechanisms of gene transcriptional regulation through analysis of high-throughput postgenomic data is one of the central problems of computational systems biology.
Husmeier, D., Lin, K.
core   +9 more sources

Transcriptional regulation of the human ALDH1A1 promoter by the oncogenic homeoprotein TLX1/HOX11 [PDF]

, 2009
The homeoprotein TLX1, which is essential to spleen organogenesis and oncogenic when aberrantly expressed in immature T cells, functions as a bifunctional transcriptional regulator, being capable of activation or repression depending on cell type and/or ...
Heidari, M., Taplin, R., Wayne Kenneth Greene, Kees, U.R., Ross Taplin, Kim Rice, Greene, W.K., Ursula Kees, Wayne Greene, Rice, K.L., Mansour Heidari   +10 more
core   +1 more source

Transcriptional Regulation and Combinatorial Genetic Logic in Synthetic Bacterial Circuits [PDF]

, 2008
We engineered several synthetic regulatory circuits to study transcriptional regulation in bacteria. We developed a new technique for DNA construction, built and characterized in vivo a library of genetic logic gates, examined the role of genetic noise ...
Cox, Robert Sidney, III
core   +1 more source

Transcriptional regulation of the urokinase receptor (u-PAR) - A central molecule of invasion and metastasis [PDF]

, 2003
The phenomenon of tumor-associated proteolysis has been acknowledged as a decisive step in the progression of cancer. This short review focuses on the urokinase receptor (u-PAR), a central molecule involved in tumor-associated invasion and metastasis ...
Fuchs, T., Allgayer, H.
core   +1 more source

Genome-wide analysis of growth phase-dependent translational and transcriptional regulation in halophilic archaea : research article [PDF]

, 2007
Background Differential expression of genes can be regulated on many different levels. Most global studies of gene regulation concentrate on transcript level regulation, and very few global analyses of differential translational efficiencies exist.
Schuster Stephan C, Lange, Christian, Oesterhelt, Dieter, Raddatz, Günter, Dieter Oesterhelt, Soppa, Jörg (Prof. Dr.), Jens Twellmeyer, Christian Lange, Soppa Jörg, Twellmeyer, Jens, Zaigler, Alexander, Oesterhelt Dieter, Jörg Soppa, Günter Raddatz, Lange, C., Raddatz Günter, Zaigler Alexander, Soppa, J., Lange Christian, Schuster, S., Zaigler, A., Schuster, Stephan C., Alexander Zaigler, Oesterhelt, D., Hammelmann Mathias, Raddatz, G., Stephan C Schuster, Mathias Hammelmann, Hammelmann, Mathias, Twellmeyer Jens, Hammelmann, M., Twellmeyer, J.   +31 more
core   +1 more source

Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet

Nature Communications, 2020
Metabolic adaptation to different diets results in changes to gene expression. Here, the authors characterise the chromatin landscape and transcriptional network in mice on a diet of high saturated fat, compared to a diet high in carbohydrate, finding a ...
Yufeng Qin, Sara A. Grimm, John D. Roberts, Kaliopi Chrysovergis, Paul A. Wade   +4 more
doaj   +1 more source

The transcriptional regulator GLYR1 may mediate NNMT down-regulation.

, 2023
The transcriptional regulator GLYR1 may mediate NNMT down-regulation.
Sarkies, Peter, Marcos Francisco Perez (11788328), Peter Sarkies (691090), Pérez, Marcos Francisco   +3 more
core   +1 more source

Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation

Nature Communications, 2019
Group 2 innate lymphoid cells (ILC2) are important mediators for allergy, but how ILC2 are regulated under chronic inflammation is still unclear. Here the authors show that Runx transcription factors, which normally suppresses ILC2 activation at steady ...
Chizuko Miyamoto, Satoshi Kojo, Motoi Yamashita, Kazuyo Moro, Georges Lacaud, Katsuyuki Shiroguchi, Ichiro Taniuchi, Takashi Ebihara   +7 more
doaj   +1 more source

Targeted deficiency of the transcriptional activator Hnf1 alpha alters subnuclear positioning of its genomic targets [PDF]

, 2008
DNA binding transcriptional activators play a central role in gene-selective regulation. In part, this is mediated by targeting local covalent modifications of histone tails.
Luco, Reini F., Sadoni, Nicolas, Maestro, Miguel A., Miguel A Maestro, Luco Reini F., Ferrer Jorge, Zink Daniele, Daniele Zink, Sadoni Nicolas, Nicolas Sadoni, Jorge Ferrer, Maestro Miguel A., Ferrer, Jorge, Reini F Luco, Zink, Daniele   +14 more
core   +2 more sources

Author Correction: Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation

Nature Communications, 2019
The original version of this Article contained an error in the author affiliations. Affiliation 5 incorrectly read ‘Laboratory for Prediction of Cell Systems Dynamics, RIKEN Center for Biosystems Dynamics Research (BDR), Suite, Hyogo 565-0874, Japan ...
Chizuko Miyamoto, Satoshi Kojo, Motoi Yamashita, Kazuyo Moro, Georges Lacaud, Katsuyuki Shiroguchi, Ichiro Taniuchi, Takashi Ebihara   +7 more
doaj   +1 more source