Results 111 to 120 of about 3,443,174 (389)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Linkages Between Mineral Element Composition of Soils and Sediments With Hyporheic Zone Dissolved Organic Matter Chemistry Across the Contiguous United States

Geophysical Research Letters
The hyporheic zone is a hotspot for biogeochemical cycling where interactions with mineral metals preserve the release and biodegradation of organic matter (OM).
J. Alan Roebuck Jr., Kenton A. Rod, Vanessa A. Garayburu‐Caruso, Rosalie K. Chu, Amy E. Goldman, Lupita Renteria, Micah Taylor, James C. Stegen   +7 more
doaj   +1 more source

Development of SOA modules in the WRF-Chem model and evaluation of the key formation pathways of SOA and associated health risk over mainland China

Environment International
Secondary Organic Aerosol (SOA), a vital component of fine particulate matter (PM2.5), formation of which is significantly affected by precursors, meteorological factors and the levels of oxidants.
Liqing Wu, Bing Wu, Zhenhao Ling, Min Shao, Xuemei Wang   +4 more
doaj   +1 more source

Simplifying microfluidic separation devices towards field-detection of blood parasites [PDF]

, 2016
With our sights set on a simple and inexpensive diagnostics device based on extraction and enrichment of parasites from human blood, we present a device design that relies on a combination of multiple different deterministic lateral displacement arrays ...
Barrett, M.P., Beech, J.P., Holm, S.H., Tegenfeldt, J.O.   +3 more
core   +3 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Modeling and solution of methane jet diffusion flames

Vetor, 2010
The aim of this work is to model a jet diffusion flame, to show the corresponding proof of existence of solutions, and to present the numerical results.
Greice da Silva Lorenzzetti, Álvaro Luiz de Bortoli, Lígia Damasceno Ferreira Marczak   +2 more
doaj   +4 more sources

Chemical abundances in Galactic planetary nebulae with Spitzer spectra [PDF]

, 2014
We present new low-resolution (R~800) optical spectra of 22 Galactic PNe with Spitzer spectra. These data are combined with recent optical spectroscopic data available in the literature to construct representative samples of compact (and presumably young)
Garcia-Hernandez, D. A., Gorny, S. K.
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Discovering chemistry to creep rupture equations in Alloy 617 with machine learning

Scientific Reports
This study seeks to discover a mathematical relationship between stress, temperature, properties, chemistry, and creep-rupture of a superalloy. This discovery will be achieved by leveraging human-supervised machine learning (ML).
Md Abir Hossain, Liangyan Hao, Wei Xiong, Calvin M. Stewart   +3 more
doaj   +1 more source

Impact of stress distribution between delta ferrite and austenite on the strain-induced martensite in AISI 304 steel

Journal of Materials Research and Technology
This study reports the influence of the fraction of δ ferrite in the austenitic stainless steel AISI 304 on strain hardening during a uniaxial tensile test. Two different steels of altered chemistry and the corresponding fractions of δ ferrite (0.5 and 7.
M. Neslušan, E. Schmidová, J. Čapek, F. Klejch, M. Krafka, S. Dobák, J. Pastorková   +6 more
doaj   +1 more source