Results 91 to 100 of about 9,418,765 (294)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Modelling solute transport in soil columns using advective-dispersive equations with fractional spatial derivatives [PDF]
, 2010 Solute transport in soils is commonly simulated with the advective–dispersive equation, or ADE. It has been reported that this model cannot take into account several important features of solute movement through soil.
San Jose Martinez, Fernando
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Optimal control of fractional systems: a diffusive formulation [PDF]
, 2010 Optimal control of fractional linear systems on a finite horizon can be classically formulated using the adjoint system. But the adjoint of a causal fractional integral or derivative operator happens to be an anti-causal operator: hence, the adjoint ...
Matignon, Denis
core
Discrete-time model reference control schemes of milling forces using fractional order holds [PDF]
, 2007 Increasing competence makes to develop and implement more complex control schemes on manufacturing environments. In this paper, a discrete time model reference control for practical milling using different discretization of the continuous-time plant is ...
M. de la Sen +3 more
core +1 more source
IEEE AccessThis paper focuses on the fractional-order modeling and analysis of single-phase quasi-Z-source rectifier (qZSR), aims to extend the single-phase qZSR from integer-order domain to fractional-order domain. Additionally, it has been demonstrated explicitly
Xiaoquan Zhu, Ziwen Chen, Bo Zhang
doaj +1 more source
Fractional Mass-Spring-Damper System Described by Generalized Fractional Order Derivatives
Fractal and Fractional, 2019 This paper proposes novel analytical solutions of the mass-spring-damper systems described by certain generalized fractional derivatives. The Liouville−Caputo left generalized fractional derivative and the left generalized fractional derivative ...
Ndolane Sene +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source