Results 81 to 90 of about 175,341 (275)

Comparison of Fractional Order Modelling and Integer Order Modelling of Fractional Order Buck Converter in Continuous Condition Mode Operation

Advances in Electrical and Electronic Engineering, 2016
Producing a mathematical model with high accuracy is the first and important step in control of systems. Nowadays fractional calculus has been in the spotlight and it has a lot of application especially in control engineering. Fractional modelling on one
Ali Moshar Movahed, Heydar Toossian Shandiz, Syed Kamal Hosseini Sani   +2 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Fractional Order Tube Model Reference Adaptive Control for a Class of Fractional Order Linear Systems

International Journal of Applied Mathematics and Computer Science, 2020
We introduce a novel fractional order adaptive control design based on the tube model reference adaptive control (TMRAC) scheme for a class of fractional order linear systems. By considering an adaptive state feedback control configuration, the main idea
Balaska Hanane, Ladaci Samir, Djouambi Abdelbaki, Schulte Horst, Bourouba Bachir   +4 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Fractional-Order Modeling and Steady-State Analysis of Single-Phase Quasi-Z-Source Pulse Width Modulation Rectifier

IEEE Access
This paper focuses on the fractional-order modeling and analysis of single-phase quasi-Z-source rectifier (qZSR), aims to extend the single-phase qZSR from integer-order domain to fractional-order domain. Additionally, it has been demonstrated explicitly
Xiaoquan Zhu, Ziwen Chen, Bo Zhang
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Realization of fractional order controllers [PDF]

Acta Montanistica Slovaca, 2003
An approach to realizations of fractional-order controllers is presented. The suggested approach is based on the use of continued fraction expansions.
O’Leary Paul, Dorcak Lubomir, Chen YangQuan, Vinagre Blas M., Podlubny Igor, Petras Ivo   +5 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Robust Stabilization of Fractional-Order Systems with Interval Uncertainties via Fractional-Order Controllers

Advances in Difference Equations, 2010
We propose a fractional-order controller to stabilize unstable fractional-order open-loop systems with interval uncertainty whereas one does not need to change the poles of the closed-loop system in the proposed method.
Sayyad Delshad Saleh, Asheghan MohammadMostafa, Hamidi Beheshti Mohammadtaghi   +2 more
doaj   +2 more sources