Results 51 to 60 of about 21,639 (263)

Finite volume element method with the WSGD formula for nonlinear fractional mobile/immobile transport equations

open access: yesAdvances in Difference Equations, 2020
In this article, a finite volume element method with the second-order weighted and shifted Grünwald difference (WSGD) formula is proposed and studied for nonlinear time fractional mobile/immobile transport equations on triangular grids. By using the WSGD
Jie Zhao   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Design and FPGA Implementation of Variable Cutoff Frequency Filter based on Continuously Variable Fractional Delay Structure and Interpolation Technique

open access: yesInternational Journal of Advances in Telecommunications, Electrotechnics, Signals and Systems, 2015
This paper presents the design and FPGA implementation of interpolated continuously variable fractional delay structure based filter (ICVFD filter) with fine control over the cutoff frequency. In the ICVFD filter, each unit delay of the prototype lowpass
Sumedh Dhabu, Achutavarrier Prasad Vinod
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Dynamic Behaviors and the Equivalent Realization of a Novel Fractional-Order Memristor-Based Chaotic Circuit

open access: yesComplexity, 2018
This paper proposed a novel fractional-order memristor-based chaotic circuit. A memristive diode bridge cascaded with a fractional-order RL filter constitutes the generalized fractional-order memristor.
Ningning Yang   +4 more
doaj   +1 more source

Passive Synthesis of Immittance for Fractional-Order Three-Element-Kind Circuit

open access: yesIEEE Access, 2019
As an interdisciplinary research area, fractional circuits and systems have attracted extensive attention of scholars and researchers for their superior performance and potential applications.
Guishu Liang, Jiawei Hao
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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