Results 91 to 100 of about 59,224 (329)

Fractional order calculus: historical apologia, basic concepts and some applications

Revista Brasileira de Ensino de Física
Fractional order calculus (FOC) deals with integrals and derivatives of arbitrary (i.e., non-integer) order, and shares its origins with classical integral and differential calculus.
S.A. David, J.L. Linares, E.M.J.A. Pallone   +2 more
doaj   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Fractional isoperimetric Noether's theorem in the Riemann-Liouville sense

, 2013
We prove Noether-type theorems for fractional isoperimetric variational problems with Riemann-Liouville derivatives. Both Lagrangian and Hamiltonian formulations are obtained. Illustrative examples, in the fractional context of the calculus of variations,
Almeida, Almeida, Atanacković, Atanacković, Baleanu, Bartosiewicz, Chen, Delfim F.M. Torres, El-Nabulsi, Ferreira, Frederico, Frederico, Frederico, Frederico, Gastão S.F. Frederico, Gelfand, Herzallah, Hilfer, Jafari, Kilbas, Kiryakova, Kiryakova, Klimek, Leitmann, Malinowska, Malinowska, Malinowska, Martins, Odzijewicz, Odzijewicz, Podlubny, Pooseh, Pooseh, Riewe, Riewe, Torres, Torres, Torres, Torres, van Brunt   +39 more
core   +1 more source

A survey on fractional variational calculus [PDF]

, 2019
This is a preprint of a paper whose final and definite form is in 'Handbook of Fractional Calculus with Applications. Vol 1: Basic Theory', De Gruyter.
Almeida, Ricardo, Torres, Delfim F. M.
openaire   +3 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Optimal random search, fractional dynamics and fractional calculus

, 2013
What is the most efficient search strategy for the random located target sites subject to the physical and biological constraints? Previous results suggested the L\'evy flight is the best option to characterize this optimal problem, however, which ...
Chen, YangQuan, Zeng, Caibin
core   +1 more source

Operators of Fractional Calculus and Their Applications [PDF]

Mathematics, 2018
n ...
openaire   +5 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

From Fractional Quantum Mechanics to Quantum Cosmology: An Overture

Mathematics, 2020
Fractional calculus is a couple of centuries old, but its development has been less embraced and it was only within the last century that a program of applications for physics started. Regarding quantum physics, it has been only in the previous decade or
Paulo Vargas Moniz, Shahram Jalalzadeh
doaj   +1 more source

Fractional Calculus of Variations for Double Integrals [PDF]

, 2011
We consider fractional isoperimetric problems of calculus of variations with double integrals via the recent modified Riemann-Liouville approach. A necessary optimality condition of Euler-Lagrange type, in the form of a multitime fractional PDE, is ...
Odzijewicz, Tatiana, Torres, Delfim F. M.   +1 more
core   +3 more sources