Results 101 to 110 of about 60,684 (330)

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

Gauge Invariant Fractional Electromagnetic Fields

, 2011
Fractional derivatives and integrations of non-integers orders was introduced more than three centuries ago but only recently gained more attention due to its application on nonlocal phenomenas.
Agrawal, Agrawal, Baleanu, Baleanu, Bauer, Belleguie, Brandt, Caputo, Caputo, Cresson, Cresson, Dreisigmeyer, Engheta, Genchev, Goldfain, Herrmann, Iomin, Ketov, Kilbas, Kusnezov, Laskin, Laskin, Lim, Magin, Mashhoon, Matheus Jatkoske Lazo, Metzler, Metzler, Munkhammar, Muslih, Naber, Naqvi, Oldham, Podlubny, Raspini, Riewe, Tarasov, Tarasov, West, Zhang, Závada   +40 more
core   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Fractional Calculus of Variations for Double Integrals [PDF]

, 2011
We consider fractional isoperimetric problems of calculus of variations with double integrals via the recent modified Riemann-Liouville approach. A necessary optimality condition of Euler-Lagrange type, in the form of a multitime fractional PDE, is ...
Odzijewicz, Tatiana, Torres, Delfim F. M.   +1 more
core   +3 more sources

Modeling anomalous diffusion and volatility in the Australian national electricity market using a space-fractional Black-Scholes framework

AIMS Mathematics
Extreme volatility, price spikes, and complex nonlinear dynamics are characteristics often shown in the electricity market, particularly the Australian national electricity market (NEM).
Doungporn Wiwatanapataphee, Yong Hong Wu, Wannika Sawangtong, Panumart Sawangtong   +3 more
doaj   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Fractional isoperimetric Noether's theorem in the Riemann-Liouville sense

, 2013
We prove Noether-type theorems for fractional isoperimetric variational problems with Riemann-Liouville derivatives. Both Lagrangian and Hamiltonian formulations are obtained. Illustrative examples, in the fractional context of the calculus of variations,
Almeida, Almeida, Atanacković, Atanacković, Baleanu, Bartosiewicz, Chen, Delfim F.M. Torres, El-Nabulsi, Ferreira, Frederico, Frederico, Frederico, Frederico, Gastão S.F. Frederico, Gelfand, Herzallah, Hilfer, Jafari, Kilbas, Kiryakova, Kiryakova, Klimek, Leitmann, Malinowska, Malinowska, Malinowska, Martins, Odzijewicz, Odzijewicz, Podlubny, Pooseh, Pooseh, Riewe, Riewe, Torres, Torres, Torres, Torres, van Brunt   +39 more
core   +1 more source

Special polynomials and fractional calculus

Mathematical and Computer Modelling, 2003
The authors state that by combining the properties of exponential operators and suitable integral representations, one can find an alternative way of treating fractional operators. Further they show that some families of special polynomials may provide a complement to the theory of fractional operators.
Luis Vázquez, Giuseppe Dattoli, Paolo Ricci, Clemente Cesarano   +3 more
openaire   +3 more sources

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

q-deformed Lie algebras and fractional calculus

, 2007
Fractional calculus and q-deformed Lie algebras are closely related. Both concepts expand the scope of standard Lie algebras to describe generalized symmetries. For the fractional harmonic oscillator, the corresponding q-number is derived.
Herrmann, Richard
core   +2 more sources