Results 51 to 60 of about 492,476 (332)

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura   +5 more
wiley   +1 more source

Bielecki-Ulam stability of a hammerstein-type difference system

open access: yesMethodsX
In this study, we investigate the Bielecki-Ulam (B-U) stabilities of two forms of Hammerstein-type difference systems (HT-DS). Specifically, we consider the systems:(0.1){xm+1−xm=M¯mxm+F¯(m,xm,xhm)[∑[j=0][m]G¯(m,j)H¯(j,xj,xhj)]x0=b0,and(0.2){xm+1−xm=M ...
Gul Rahmat   +5 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Analysis of relative controllability and finite-time stability in nonlinear switched fractional impulsive systems

open access: yesAIMS Mathematics
This article investigated a class of switched impulsive fractional control systems with delays occurring at different time instants in both the state and control input.
P. K. Lakshmi Priya   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

On New Unified Bounds for a Family of Functions via Fractional q-Calculus Theory

open access: yesJournal of Function Spaces, 2020
The present article deals with the new estimates in q-calculus and fractional q-calculus on a time scale Tt0=0∪t:t=t0qn,n is a nonnegative integer, where t0∈ℝ and ...
Li Xu   +4 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

On the Rigorous Correspondence Between Operator Fractional Powers and Fractional Derivatives via the Sonine Kernel

open access: yesFractal and Fractional
Traditional operational calculus, while intuitive and effective in addressing problems in physical fractal spaces, often lacks the rigorous mathematical foundation needed for fractional operations, sometimes resulting in inconsistent outcomes. To address
Zelin Liu, Xiaobin Yu, Yajun Yin
doaj   +1 more source

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