Results 151 to 160 of about 1,884 (305)

Necessary and sufficient conditions for the fractional calculus of variations with Caputo derivatives [PDF]

, 2010
Ricardo Almeida, Delfim F. M. Torres
openalex   +1 more source

Fractional calculus analysis of the cosmic microwave background [PDF]

, 2012
Cosmic microwave background (CMB) radiation is the imprint from an early stage of the Universe and investigation of its properties is crucial for understanding the fundamental laws governing the structure and evolution of the Universe.
Tintareanu, Ovidiu, Petruta Stefanescu, Stefanescu, Petruta, Baleanu, Dumitru, Ovidiu Tintareanu, J. A. Tenreiro Machado, Dumitru Baleanu, Machado, J. A. Tenreiro   +7 more
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Analysis and numerical approximation of tempered fractional calculus of variations problems

, 2019
Ricardo Almeida, M. Luísa Morgado
openalex   +2 more sources

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Generalized k-variations and Hurst parameter estimation for the fractional wave equation via Malliavin calculus [PDF]

, 2019
Radomyra Shevchenko, Meryem Slaoui, Ciprian A. Tudor   +2 more
openalex   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Existence of chaos and the approximate solution of the Lorenz–Lü–Chen system with the Caputo fractional operator

AIP Advances
Dynamical systems and fractional differential equations can be modeled using variable-order differential operators. In this study, the dynamics of a variable-order fractional Lorenz–Lü–Chen system with variable-order and constant-order derivatives are ...
Najat Almutairi, Sayed Saber
doaj   +1 more source