Results 111 to 120 of about 857,826 (292)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Generalized multiplicative h-fractional integrals and derivatives with Hermite-Hadamard inequality

Journal of Inequalities and Applications
In this study, we introduce new generalized multiplicative h-fractional integral and h-fractional derivative operators by employing multiplicative calculus within the framework of fractional analysis.
Umut Bas, Huseyin Yildirim
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Fractional calculus for distributions

Fractional derivatives and integrals for measures and distributions are reviewed. The focus is on domains and co-domains for translation invariant fractional operators. Fractional derivatives and integrals interpreted as -convolution operators with power
Kleiner, Tillmann, Hilfer, Rudolf
core   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Starlikeness and convexity of fractional calculus operators

, 2009
The main object of the present paper is to investigate the starlikeness and convexity of certain general families of operators of fractional calculus (that is, fractional integral and fractional derivative).
Choi, J. H., Kim, Y. C., Srivastava, H.M.   +2 more
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

A fractal-fractional gingerbread-man map generalized by p−fractal-fractional difference operator

Қарағанды университетінің хабаршысы. Математика сериясы
By using the generalization of the gamma function (p−gamma function: Γp(.)), we introduce a generalization of the fractal-fractional calculus which is called p−fractal-fractional calculus. Examples are illustrated including the basic power functions. As
R.W. Ibrahim, S. Momani
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

About one method of approximate solution of the first boundary value problem for the fractional diffusion equation

Discrete and Continuous Models and Applied Computational Science
Background This article focuses on a rapidly developing area of fractional calculus that describes anomalous diffusion. Since the correct form of the fractional-order equation describing anomalous diffusion - remains an open question, the authors use ...
Ivan I. Zakharov, Temirkhan S. Aleroev
doaj   +1 more source