Results 71 to 80 of about 104,516 (286)
Molecular ions in the protostellar shock L1157-B1 [PDF]
, 2014 We perform a complete census of molecular ions with an abundance larger than 1e-10 in the protostellar shock L1157-B1 by means of an unbiased high-sensitivity survey obtained with the IRAM-30m and Herschel/HIFI. By means of an LVG radiative transfer code
Bachiller, R. +4 more
core +3 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Volatile inventories in clathrate hydrates formed in the primordial nebula
, 2010 Examination of ambient thermodynamic conditions suggest that clathrate hydrates could exist in the martian permafrost, on the surface and in the interior of Titan, as well as in other icy satellites.
Cordier, D. +3 more
core +4 more sources
Ionization fraction and the enhanced sulfur chemistry in Barnard 1 [PDF]
, 2016 Barnard B1b has revealed as one of the most interesting globules from the chemical and dynamical point of view. It presents a rich molecular chemistry characterized by large abundances of deuterated and complex molecules.
Aguado, A. +9 more
core +4 more sources
Hand Rejuvenation by Ablative Fraction CO2 Laser
Journal of Skin and Stem Cell, 2014 Background: Ablative fractional CO2 laser (AFCL) has been reported to be safe and effective to use for preventing hand photoaging in a recent pilot study. Objectives: This study aimed to evaluate the efficacy of AFCL in improvement of hand photoaging in 25 patients. Patients and Methods: A prospective, before- after, single blind study was conducted in
Elham Behrangi +5 more
openaire +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Lactate: brain fuel in human traumatic brain injury: a comparison with normal healthy control subjects. [PDF]
, 2015 We evaluated the hypothesis that lactate shuttling helps support the nutritive needs of injured brains. To that end, we utilized dual isotope tracer [6,6-(2)H2]glucose, that is, D2-glucose, and [3-(13)C]lactate techniques involving arm vein tracer ...
Brooks, George A +6 more
core +1 more source
Carbon Isotope Fractionation in the System CO2(gas)—CO2(aqueous)—HCO3−(aqueous) [PDF]
Nature, 1967 Carbon isotope fractionation between gaseous carbon dioxide and aqueous bicarbonate decreases from 9.2 to 6.8 parts per thousand over the temperature range 0°–30° C. This fractionation occurs in the hydration stage, not in the passage of atmospheric carbon dioxide through the air–water interface.
W. G. DEUSER, E. T. DEGENS
openaire +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source