Results 121 to 130 of about 187,262 (303)
Computation of fractional derivatives using Fourier transform and digital FIR differentiator [PDF]
, 2000 Chien–Cheng Tseng +2 more
openalex +1 more source
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
Molecular Oncology, EarlyView.NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi +5 more
wiley +1 more source
Fractal and FractionalIn magnetic data processing, a fractional derivative can enhance details without excessively amplifying high-frequency noise. To obtain a fractional derivative numerically, a large number of survey points are required. This article demonstrates how a few
Ruijian Wang, Yangyi Sui
doaj +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
A New fractional derivative for differential equation of fractional order under interval uncertainty
Advances in Mechanical Engineering, 2015 In this article, we develop a new definition of fractional derivative under interval uncertainty. This fractional derivative, which is called conformable fractional derivative , inherits some interesting properties from the integer differentiability ...
Soheil Salahshour +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Optimal design for fractional-order active isolation system
Advances in Mechanical Engineering, 2015 The optimal control of fractional-order active isolation system is researched based on the optimal control theory, and the effect of fractional-order derivative on passive isolation system is also analyzed.
Hao You, Yongjun Shen, Shaopu Yang
doaj +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Space-time estimates of linear flow and application to some nonlinear integro-differential equations corresponding to fractional-order time derivative [PDF]
, 2002 Hitoshi Hirata, Changxing Miao
openalex +1 more source