Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
New definition of fractional derivative included Mittag-Leffler function of conformable type [PDF]
Mathematics and Computational SciencesIn this paper a new definitionn of fractional derivative and fractional integral in the sense ofconformable derivative type is presented. This form of definition shows that it is more compatible withclassical natural definition of derivative and is more ...
Reza Danaei
doaj +1 more source
Fractal and Fractional, 2020 This paper proposes the analytical solution for a class of the fractional diffusion equation represented by the fractional-order derivative. We mainly use the Grunwald–Letnikov derivative in this paper.
Ndolane Sene
doaj +1 more source
Analytical Solutions of the Predator–Prey Model with Fractional Derivative Order via Applications of Three Modified Mathematical Methods [PDF]
, 2023 Mounirah Areshi +4 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
AIMS Mathematics, 2022 In this paper, the solutions of some typical nonlinear fractional differential equations are discussed, and the implicit analytical solutions are obtained.
Zhoujin Cui
doaj +1 more source
A new truncated $M$-fractional derivative type unifying some fractional derivative types with classical properties [PDF]
, 2017 We introduce a truncated $M$-fractional derivative type for $\alpha$-differentiable functions that generalizes four other fractional derivatives types recently introduced by Khalil et al., Katugampola and Sousa et al., the so-called conformable ...
de Oliveira, E. Capelas +1 more
core +3 more sources
Robust stabilization of interval fractional‐order plants with an interval time delay by fractional‐order proportional integral derivative controllers [PDF]
, 2023 Majid Ghorbani +2 more
openalex +1 more source