Results 141 to 150 of about 39,478 (331)

A pseudo-spectral approach for optimal control problems of variable-order fractional integro-differential equations

open access: yesAIMS Mathematics
Nonlinear optimal control problems governed by variable-order fractional integro-differential equations constitute an important subgroup of optimal control problems. This group of problems is often difficult or impossible to solve analytically because of
Zahra Pirouzeh   +3 more
doaj   +1 more source

Robust Tilt-Integral-Derivative Controllers for Fractional-Order Interval Systems [PDF]

open access: gold, 2023
Muhammad Zeeshan Malik   +3 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Applications of Fractional-Order Calculus in Robotics

open access: yesFractal and Fractional
Fractional calculus, a branch of mathematical analysis, extends traditional calculus that encompasses integrals and derivatives of non-integer orders [...]
Abhaya Pal Singh, Kishore Bingi
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Fractional Milne-type inequalities for twice differentiable functions

open access: yesAIMS Mathematics
In this study, a specific identity was derived for functions that possess two continuous derivatives. Through the utilization of this identity and Riemann-Liouville fractional integrals, several fractional Milne-type inequalities were established for ...
Areej A. Almoneef   +3 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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