Results 141 to 150 of about 2,428 (290)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Fractional boundary value problems with multiple orders of fractional derivatives and integrals
, 2017 In this article we study a new class of boundary value problems for fractional differential equations and inclusions with multiple orders of fractional derivatives and integrals, in both fractional differential equation and boundary conditions.
Jessada Tariboon, Sotiris K. Ntouyas
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
On a new class of Hardy-type inequalities with fractional integrals and fractional derivatives
, 2014 This paper is devoted to a new class of general weighted Hardy-type inequalities for arbitrary convex functions with some applications to different type of fractional integrals and fractional ...
Sajid Iqbal +5 more
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Generalized fractional derivatives generated by a class of local proportional derivatives
, 2018 Recently, Anderson and Ulness [Adv. Dyn. Syst. Appl. 10, 109 (2015)] utilized the concept of the proportional derivative controller to modify the conformable derivatives. In parallel to Anderson’s work, Caputo and Fabrizio [Progr. Fract. Differ. Appl. 1,
Thabet Abdeljawad +2 more
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
A comprehensive study on Ostrowski-type inequalities: multiplicative conformable fractional integrals approach [PDF]
Surveys in Mathematics and its ApplicationsIn this paper, we first recall the concept o f the multiplicative conformable fractional integrals (MCFI) and their several properties. Then, we establish the Ostrowski type inequalities in two distinct senses for multiplicative conformable fractional ...
Büşra Betül Ergün, Hüseyin Budak
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