Results 91 to 100 of about 8,933,709 (332)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Consumption and fractional differencing: old and new anomalies [PDF]

open access: yes
A calculation of the stochastic properties of consumption when income follows a fractional stochastic process, showing how this may explain excess-smoothness results noted in previous studies.Consumption (Economics) ; Income ; Time-series ...
Joseph G. Haubrich
core  

A brief history of long memory: Hurst, Mandelbrot and the road to ARFIMA [PDF]

open access: yes, 2016
Long memory plays an important role in many fields by determining the behaviour and predictability of systems; for instance, climate, hydrology, finance, networks and DNA sequencing.
Franzke, Christian   +3 more
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Air Pollution in 88 US Metropolitan Areas: Trends and Persistence

open access: yesAtmosphere
This paper analyses trends and persistence in air pollution levels in 88 US metropolitan areas using fractional integration methods. The results indicate that the differencing parameter d is higher than 0 in 38 of the series, which supports the ...
Guglielmo Maria Caporale   +3 more
doaj   +1 more source

Sesgos en estimación, tamaño y potencia de una prueba sobre el parámetro de memoria larga en modelos ARFIMA

open access: yesLecturas de Economía, 2011
Sesgos en estimación, tamaño y potencia de una prueba sobre el parámetro de memoria larga en modelos ARFIMA   Resumen: Castaño et al. (2008) proponen una prueba para investigar la existencia de memoria larga, basada en el parámetro de diferenciación ...
Elkin Castaño Vélez   +2 more
doaj   +1 more source

A Recursive Algorithm For Fractionally Differencing Long Data Series

open access: yesJournal of Modern Applied Statistical Methods, 2003
We propose a recursive algorithm to fractionally difference time series data. The algorithm eliminates the need to evaluate the gamma function directly, and hence avoids the overflow problem that arises when fractionally differencing a long data series. The proposed algorithm can be implemented using any general matrix programming language.
Joseph McCarthy   +2 more
openaire   +2 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Real exchange rates in latin america: The ppp hypothesis and fractional integration [PDF]

open access: yes, 2008
This paper tests for PPP in a group of seventeen Latin American (LA) countries by applying fractional integration techniques to real exchange rate series. Compared to earlier studies on these economies, this approach has the advantage of allowing for non-
Caporale, GM
core  

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