Results 61 to 70 of about 11,523 (297)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

A Novel Generalized Time-Stepping Scheme for Time-Fractional Reaction–Diffusion Models Using a New Rational Function Approximation of Mittag-Leffler Functions

Axioms
The Mittag-Leffler function holds significant importance in fractional calculus due to its extensive applications in addressing challenges across science, engineering, biology, hydrology, and earth sciences.
Madushi U. Wickramasinghe, Olaniyi S. Iyiola   +1 more
doaj   +1 more source

Advanced numerical simulations of lid-driven cavity flows using an optimized parallelized fractional step method [PDF]

Computational Algorithms and Numerical Dimensions
This work presents a numerical simulation of lid-driven cavity flows by solving the incompressible Navier-Stokes equations, with results validated against established benchmarks. The developed code uses a fractional step method combined with second-order
Muhammad Abid, Tayyaba Akhtar, Mohamed M. Awad, Muhammad Imran   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Persistence and cycles in US hours worked [PDF]

, 2012
This paper analyses monthly hours worked in the US over the sample period 1939m1 – 2011m10 using a cyclical long memory model; this is based on Gegenbauer processes and characterised by autocorrelations decaying to zero cyclically and at a hyperbolic ...
Caporale, GM, Gil-Alana, LA
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Exogenous shocks and time-varying price persistence in the EU27

Journal of Applied Economics
This paper analyses monthly price persistence in the EU27 countries over the period 2010–2022 using a fractional integration framework, where the measure of persistence is the fractional differencing parameter d.
Guglielmo Maria Caporale, Luis A. Gil-Alana, Amir Imeri   +2 more
doaj   +1 more source

Deterministic Versus Stochastic Seasonal Fractional Integration and structural breaks [PDF]

, 2007
This paper considers a general model which allows for both deterministic and stochastic forms of seasonality, including fractional (stationary and nonstationary) orders of integration, and also incorporating endogenously determined structural breaks ...
Caporale, GM, Cunado, J, Gil-Alana, LA
core   +1 more source

Persistence in youth unemployment [PDF]

, 2012
This paper examines the degree of persistence of youth unemployment (total, male and female) in twenty-four countries by using two alternative measures: the AR coefficient and the fractional differencing parameter, based on short- and long-memory ...
Caporale, GM, Gil-Alana, LA
core   +2 more sources