Results 111 to 120 of about 2,668,291 (311)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Symmetry Analysis and Wave Solutions of Time Fractional Kupershmidt Equation

open access: yesJournal of Applied Mathematics
This study employs the Lie symmetry technique to explore the symmetry features of the time fractional Kupershmidt equation. Specifically, we use the Lie symmetry technique to derive the symmetry generators for this equation, which incorporates a ...
Shalu Saini, Rajeev Kumar, Kamal Kumar
doaj   +1 more source

Regularization of differential equations by fractional noise

open access: yesStochastic Processes and their Applications, 2002
Existence and uniqueness of a strong solution to the differential equation \[ X_t= x + \int _0^t b(s,X_s)\,ds + B^H_t, \quad t\geq 0, \] is established, where \(B^H_t\) is a fractional Brownian motion with the Hurst parameter \(H\in (0,1)\) and \(b(s,x)\) is a bounded Borel function with at most linear growth in \(x\) (for \(H\leq 1/2\)) or Hölder ...
Nualart, David, Ouknine, Youssef
openaire   +1 more source

Multidimensional fractional Schrödinger equation

open access: yes, 2012
This work is intended to investigate the multi-dimensional space-time fractional Schrödinger equation of the form ħ ⁠, with ħ the Planck's constant divided by 2π, m is the mass and u(t,x) is a wave function of the particle.
M. M. Rodrigues   +3 more
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Solution of Black-Scholes Fractional Partial Differential Equation with two Assets by Aboodh Decomposition Method.

open access: yes, 2019
In this paper, we present the solution of Black-Scholes fractional partial differential equation with two assets in the Caputo fractional derivative sense by the Aboodh decomposition method.
Alfaqeih, S.   +3 more
core   +1 more source

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