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Numerical modelling and simulation in sheet metal forming [PDF]
Journal of Materials Processing Technology, 2004 The application of numerical modelling and simulation in manufacturing technologies is looking back over about a 20–30 years history. In recent years, the role of modelling and simulation in engineering and in manufacturing industry has been continuously
Altan +8 more
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SFlex-WMS: a novel multi-expert system for flexible logistics and warehouse operation in the context of Industry 4.0 [PDF]
SHS Web of Conferences, 2021 Production lines form the backbone of a manufacturing plant while the warehouse is the heart that pumps the supplies through logistics veins. However, logistics issues among manufacturing industries are well known for causing downstream production ...
Ng Sokchoo +3 more
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Journal of Translational Medicine, 2023 Background In drug development, few molecules from a large pool of early candidates become successful medicines after demonstrating a favourable benefit-risk ratio.
Chao Chen +4 more
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The area under the effect curve as an efficacy determinant for anti‐infectives
CPT: Pharmacometrics & Systems Pharmacology, 2022 Pharmacokinetic/pharmacodynamic (PK/PD) indices making use of area under the curve, maximum concentration, and the duration that in vivo drug concentration is maintained above a critical level are commonly applied to clinical dose prediction from animal ...
Chao Chen +2 more
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‘Falling heads’: investigating reflexive responses to head–neck perturbations
BioMedical Engineering OnLine, 2022 Background Reflexive responses to head–neck perturbations affect the injury risk in many different situations ranging from sports-related impact to car accident scenarios.
Isabell Wochner +3 more
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Frontiers in Bioengineering and Biotechnology, 2023 Introduction: A common hand injury in American football, rugby and basketball is the so-called jersey finger injury (JFI), in which an eccentric overextension of the distal interphalangeal joint leads to an avulsion of the connected musculus flexor ...
Lennart V. Nölle +4 more
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Pharmacology Research & Perspectives, 2022 Treatment response to clopidogrel is associated with CYP2C19 activity through the formation of the active H4 metabolite. The aims of this study were to develop a physiologically based pharmacokinetic (PBPK) model of clopidogrel and its metabolites for ...
Janna K. Duong +4 more
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IEEE Computer Architecture Letters, 2021 Computer architects extensively use simulation to steer future processor research and development. Simulating large-scale multicore processors is extremely time-consuming and is sometimes impossible because of simulation infrastructure limitations. This paper proposes scale-model simulation, a novel methodology to predict large-scale multicore system ...
Wenjie Liu 0015 +4 more
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Reusability of simulation models [PDF]
Knowledge-Based Systems, 1996 Modelling and simulation are widely used methods in design and other engineering tasks. Providing libraries of reusable model fragments is a promising way of supporting engineering modelling. The paper discusses means of structuring such libraries in a generic and reusable way.
Pos, A. +3 more
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Modelling and simulation: An overview [PDF]
Mathematics and Computers in Simulation, 2013 The papers in this special issue of Mathematics and Computers in Simulation cover the following topics: improving judgmental adjustment of model-based forecasts, whether forecast updates are progressive, on a constrained mixture vector autoregressive model, whether all estimators are born equal: the empirical properties of some estimators of long ...
McAller, M., Chan, F., Oxley, L.
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