Engineering Hybrid Extracellular Vesicles for Functional mRNA Delivery
This study optimizes two methods for the generation of extracellular vesicle (EV)‐mimetic‐Lipid Nanoparticle (LNP) (CELLNPs) and EV‐LNP (HEVs) hybrid nanoparticles for messenger (mRNA) delivery. The authors screen lipid compositions to maximize hybrid nanoparticle formation and analyze the resulting nanoparticles with single particle characterization ...
Ana Filipa Louro +6 more
wiley +1 more source
Optical solutions to the time fractional Akbota equation arising in nonlinear optics via two distinct methods. [PDF]
Mahmood SS +3 more
europepmc +1 more source
Defect Analysis of the β– to γ–Ga2O3 Phase Transition
The role of defects at all the relevant stages of the β$\beta$‐ to γ$\gamma$‐Ga2O3 polymorph transition is investigated using a multi method approach. The positron annihilation spectroscopy based results show that the defect density decreases after the transition, and that changes in defect configuration within the γ phase occur with increasing ...
Umutcan Bektas +9 more
wiley +1 more source
Stochastic fractional order model for the computational analysis of computer virus. [PDF]
Ayaz A +8 more
europepmc +1 more source
Bright Monocompound Metal Halide Scintillator for Fast Neutron Radiography
Metal halide scintillator, tetraphenylphosphonium manganese bromide (TPP2MnBr4), provides a significant benefit for fast neutron imaging. A fourfold increase in efficiency over traditional zinc sulfide screens is achieved by efficiently utilizing neutron interactions within its homogeneous structure.
Aditya Bhardwaj +13 more
wiley +1 more source
Soliton solutions with bifurcation, sensitivity, chaotic and stability analysis of the (2+1)-dimensional Zoomeron equation using generalized Riccati equation mapping method. [PDF]
Zainab A +5 more
europepmc +1 more source
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Unsteady two dimensional flow of non-newtönian fractional Casson fluid for an edge with heated boundaries. [PDF]
Nadeem S +4 more
europepmc +1 more source
Charge carrier concentration and mobility in TiO2, ZrO2, and HfO2 powder films are experimentally mapped as a function of temperature. The results uncover polaron‐mediated transport regimes and field‐activated conduction, enabling the design of oxide‐based electronic and energy devices with thermally tunable functionality.
Beatriz Moura Gomes +3 more
wiley +1 more source
Dynamical study of different types of soliton solutions with bifurcation, chaos and sensitivity analysis to the non-linear coupled Schrödinger model. [PDF]
Nasir R +5 more
europepmc +1 more source

