A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham +7 more
wiley +1 more source
Physics-Informed Neural Network-Based Inverse Framework for Time-Fractional Differential Equations for Rheology. [PDF]
Biology (Basel)Thakur S, Mitra H, Ardekani AM.
europepmc +1 more source
Arthritis Care &Research, EarlyView.Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada +7 more
wiley +1 more source
High performance adaptive step size fractional numerical scheme for solving fractional differential equations. [PDF]
Sci RepShams M, Alalyani A.
europepmc +1 more source
Data for numerical solution of Caputo's and Riemann-Liouville's fractional differential equations. [PDF]
Data Brief, 2020 Betancur-Herrera DE, Muñoz-Galeano N.
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Fractional Differential Equations
, 2017 Fractional calculus, the branch of mathematics dealing with derivatives and integrals of non-integer order, began as a mere mathematical curiosity during the time of Leibniz but through the years has developed into a very dynamic field of research. Famous mathematicians such as Riemann, Liouville, Grunwald, Euler, Lagrange, Caputo and others laid the ...
openaire +1 more source
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Arthritis Care &Research, EarlyView.Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Attributes of residual neural networks for modeling fractional differential equations. [PDF]
HeliyonAgarwal S, Mishra LN.
europepmc +1 more source
Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?
Arthritis Care &Research, EarlyView.Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet +11 more
wiley +1 more source
On the solutions of fractional differential equations with modified Mittag-Leffler kernel and Dirac Delta function: Analytical results and numerical simulations. [PDF]
PLoS OneAl-Refai M, Baleanu D, Alomari AK.
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