Results 111 to 120 of about 29,097 (308)

Generalized Fixed Point Results with Application to Nonlinear Fractional Differential Equations

, 2020
The main objective of this paper is to introduce the ( α , β )-type ϑ -contraction, ( α , β )-type rational ϑ -contraction, and cyclic ( α - ϑ ) contraction.
Hoda A. Fouad, Jamshaid Ahmad, Snezhana Hristova, Hanadi Zahed   +3 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Variational Methods for an Impulsive Fractional Differential Equations with Derivative Term

, 2019
This paper is devoted to studying the existence of solutions to a class of impulsive fractional differential equations with derivative dependence. The used technical approach is based on variational methods and iterative methods.
Haibo Chen, Jiafa Xu, Yulin Zhao
core   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Stability Results for a Coupled System of Impulsive Fractional Differential Equations

, 2019
In this paper, we establish sufficient conditions for the existence, uniqueness and Ulam–Hyers stability of the solutions of a coupled system of nonlinear fractional impulsive differential equations. The existence and uniqueness results are carried
Yujun Cui, Jiafa Xu, Zeeshan Ali, Akbar Zada, Shaheen Fatima   +4 more
core   +1 more source

Qualitative Analysis of Multi-Terms Fractional Order Delay Differential Equations via the Topological Degree Theory

, 2020
With the help of the topological degree theory in this manuscript, we develop qualitative theory for a class of multi-terms fractional order differential equations (FODEs) with proportional delay using the Caputo derivative.
Michal Fečkan, Rahmat Ali Khan, Muhammad Sher, Kamal Shah   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Representations of Solutions of Time-Fractional Multi-Order Systems of Differential-Operator Equations

Fractal and Fractional
This paper is devoted to the general theory of systems of linear time-fractional differential-operator equations. The representation formulas for solutions of systems of ordinary differential equations with single (commensurate) fractional order is known
Sabir Umarov
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source